Immunoinformatics and its relevance to understanding human immune disease

V Brusic, N Petrovsky - Expert review of clinical immunology, 2005 - Taylor & Francis
Immunology research is characterized by the production of increasingly vast amounts of
data, fuelled by genomics and proteomics projects and large-scale screening of pathogen …

Characterization and optimization of gold nanoparticle-based silver-enhanced immunoassays

S Gupta, S Huda, PK Kilpatrick, OD Velev - Analytical Chemistry, 2007 - ACS Publications
Silver-enhanced nanoparticle-labeled immunoassays provide a simple, low-cost, and
effective way of detecting antigens in dilute solutions. The physical mechanisms behind their …

Mathematical modeling of bioassays

DV Sotnikov, AV Zherdev, BB Dzantiev - Biochemistry (Moscow), 2017 - Springer
The high affinity and specificity of biological receptors determine the demand for and the
intensive development of analytical systems based on use of these receptors. Therefore …

[HTML][HTML] Rival approaches to mathematical modelling in immunology

SM Andrew, CTH Baker, GA Bocharov - Journal of Computational and …, 2007 - Elsevier
In order to formulate quantitatively correct mathematical models of the immune system, one
requires an understanding of immune processes and familiarity with a range of …

Computational modeling of immune system of the fish for a more effective vaccination in aquaculture

A Madonia, C Melchiorri, S Bonamano… - …, 2017 - academic.oup.com
Motivation A computational model equipped with the main immunological features of the sea
bass (Dicentrarchus labrax L.) immune system was used to predict more effective …

Rapid Detection of Lipopolysaccharide and Whole Cells of Francisella tularensis Based on Agglutination of Antibody-Coated Gold Nanoparticles and Colorimetric …

NA Byzova, AV Zherdev, AA Gorbatov, AG Shevyakov… - Micromachines, 2022 - mdpi.com
The paper presents development and characterization of a new bioanalytical test system for
rapid detection of lipopolysaccharide (LPS) and whole cells of Francisella tularensis, a …

Detection limits of immunoanalytical systems: Limiting factors and methods of reduction

AV Zherdev, BB Dzantiev - Journal of Analytical Chemistry, 2022 - Springer
One of the priority directions in the development of modern immunoanalytical systems is a
reliable determination of analytes in very low concentrations. In this regard, an assessment …

Deciphering Immunodiffusion: In Silico Optimization for Faster Protein Diagnostics

C Liu, S Corrie, K Regenauer-Lieb, M Hu - Talanta, 2024 - Elsevier
Immunodiffusion tests offer a simple yet powerful method for detecting protein antigens, but
their long assay times hinder clinical utility. We unveil the complex interplay of parameters …

Molecular immunology databases and data repositories

V Brusic, J Zeleznikow, N Petrovsky - Journal of immunological methods, 2000 - Elsevier
Over recent years databases have become an extremely important resource for biomedical
research. Immunology research is increasingly dependent on access to extensive biological …

Immunoinformatics—the new kid in town

V Brusic, N Petrovsky - … : Bioinformatic Strategies for Better …, 2003 - Wiley Online Library
The astounding diversity of immune system components (eg immunoglobulins, lymphocyte
receptors, or cytokines) together with the complexity of the regulatory pathways and network …