Lipids, as the basic component of cell membranes, play an important role in human health
as well as brain function. The brain is highly enriched in lipids, and disruption of lipid …

Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and
replacing them with polyunsaturated fatty acids (PUFAs) n–3 (omega–3) and n–6 (omega …

Docosahexaenoic acid (DHA), a polyunsaturated fatty acid (PUFA) enriched in
phospholipids in the brain and retina, is known to play multi-functional roles in brain health …

Cellular membranes are composed of numerous kinds of glycerophospholipids with different
combinations of polar heads at the sn-3 position and acyl moieties at the sn-1 and sn-2 …

The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and
brain development throughout the life cycle is fundamental. DHA and AA are long-chain …

Background A major challenge for lipidomic analyses is the handling of the large amounts of
data and the translation of results to interpret the involvement of lipids in biological systems …

Alzheimer's disease (AD) is a neurodegenerative disorder that is one of the most
devastating and widespread diseases worldwide, mainly affecting the aging population. One …

Modulation of membrane lipid composition and organization is currently developing as an
effective therapeutic strategy against a wide range of diseases, including cancer. This field …

Cholesterol crystalline domains characterize atherosclerotic membranes, altering vascular
signaling and function. Omega-3 fatty acids reduce membrane lipid peroxidation and …