Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: a systematic review for the EAACI guidelines

I Agache, Y Song, P Alonso‐Coello, Y Vogel, C Rocha… - Allergy, 2021 - Wiley Online Library
This systematic review evaluates the efficacy and safety of biologicals for chronic
rhinosinusitis with nasal polyps (CRSwNP) compared with the standard of care. PubMed …

Chronic rhinosinusitis: epidemiology and burden of disease

AS DeConde, ZM Soler - American journal of rhinology & …, 2016 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is based on sinonasal symptoms coupled with
sinonasal tissue inflammation. Establishing the epidemiology and prevalence of CRS …

Executive summary of EPOS 2020 including integrated care pathways.

WJ Fokkens, VJ Lund, C Hopkins, PW Hellings, R Kern… - Rhinology, 2020 - europepmc.org
The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of
similar evidence based position papers published in 2005 and 2007 and 2012 (1-3). The …

Development and validation of combined symptom‐medication scores for allergic rhinitis

B Sousa‐Pinto, LF Azevedo, M Jutel, I Agache… - Allergy, 2022 - Wiley Online Library
Background Validated combined symptom‐medication scores (CSMSs) are needed to
investigate the effects of allergic rhinitis treatments. This study aimed to use real‐life data …

Patient-reported outcome measures for adult chronic rhinosinusitis: a systematic review and quality assessment

L Rudmik, C Hopkins, A Peters, TL Smith… - Journal of Allergy and …, 2015 - Elsevier
Background With a focus on patient-centered care, there is increasing policy interest in
patient-reported outcome measures (PROMs) to inform improvements in health care …

Cost utility analysis of dupilumab versus endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps

GA Scangas, AW Wu, JY Ting, R Metson… - The …, 2021 - Wiley Online Library
Objective Both endoscopic sinus surgery (ESS) and biologic therapies have shown
effectiveness for medically‐refractory chronic rhinosinusitis with nasal polyps (CRSwNP) …

Impact of cystic fibrosis transmembrane conductance regulator therapy on chronic rhinosinusitis and health status: deep learning CT analysis and patient-reported …

DM Beswick, SM Humphries… - Annals of the …, 2022 - atsjournals.org
Rationale: Elexacaftor, tezacaftor, and ivacaftor (ETI) in triple combination improves
pulmonary health for people with cystic fibrosis (PwCF). However, its impact on objective …

Dupilumab‐induced eosinophilia in patients with diffuse type 2 chronic rhinosinusitis

FS Ryser, A Yalamanoglu, A Valaperti, C Brühlmann… - Allergy, 2023 - Wiley Online Library
Background Dupilumab, a monoclonal anti‐IL‐4Rα antibody, is approved for several type 2
mediated inflammatory diseases like asthma, atopic dermatitis, and diffuse type 2 chronic …

Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach–ARIA‐EAACI Task Force Report

J Bousquet, MH Shamji, JM Anto, HJ Schünemann… - Allergy, 2023 - Wiley Online Library
Biomarkers for the diagnosis, treatment and follow‐up of patients with rhinitis and/or asthma
are urgently needed. Although some biologic biomarkers exist in specialist care for asthma …

The functional and psychological burden of empty nose syndrome

J Manji, JV Nayak, A Thamboo - International forum of allergy & …, 2018 - Wiley Online Library
Background Empty nose syndrome (ENS) is a debilitating disorder thought to arise as a
postsurgical phenomenon from excessive loss of nasal tissues. Affected patients often report …