Cognitive impairment is a common and devastating manifestation of multiple sclerosis (MS).
Although disease-modifying therapies have been efficacious for reducing relapse rates in …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

Background Post-COVID syndrome is a severe long-term complication of COVID-19.
Although fatigue and cognitive complaints are the most prominent symptoms, it is unclear …

Importance Cognitive impairment is a common and disabling feature of multiple sclerosis
(MS), but a precise characterization of cognitive phenotypes in patients with MS is lacking …

Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

Although multiple sclerosis has traditionally been considered a white matter disease,
extensive research documents the presence and importance of grey matter injury including …

The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …

Exercise is increasingly recommended as a supportive therapy for people with Multiple
Sclerosis (pwMS). While clinical research has still not disclosed the real benefits of exercise …

The complement system is implicated in synapse loss in the MS hippocampus, but the
functional consequences of synapse loss remain poorly understood. Here, in post-mortem …

Animal models of multiple sclerosis (MS), specifically experimental autoimmune
encephalomyelitis (EAE), have been used extensively to develop anti-inflammatory …