The behaviour and ecology of the zebrafish, Danio rerio

R Spence, G Gerlach, C Lawrence… - Biological reviews, 2008 - Wiley Online Library
The zebrafish Danio rerio, is an important model organism in developmental genetics,
neurophysiology and biomedicine, but little is known about its natural ecology and …

Myostatin: a skeletal muscle chalone

SJ Lee - Annual review of physiology, 2023 - annualreviews.org
Myostatin (GDF-8) was discovered 25 years ago as a new transforming growth factor-β
family member that acts as a master regulator of skeletal muscle mass. Myostatin is made by …

Stress and growth

B Sadoul, MM Vijayan - Fish physiology, 2016 - Elsevier
1. Introduction 2. A Conceptual Framework for Growth 2.1. The Dynamic Energy Budget
(DEB) Model for Growth 2.2. Myocyte Growth 3. Stress Effect on Energy Available for Growth …

Generation of Myostatin Gene-Edited Channel Catfish (Ictalurus punctatus) via Zygote Injection of CRISPR/Cas9 System

K Khalil, M Elayat, E Khalifa, S Daghash, A Elaswad… - Scientific reports, 2017 - nature.com
The myostatin (MSTN) gene is important because of its role in regulation of skeletal muscle
growth in all vertebrates. In this study, CRISPR/Cas9 was utilized to successfully target the …

Clinical, agricultural, and evolutionary biology of myostatin: a comparative review

BD Rodgers, DK Garikipati - Endocrine reviews, 2008 - academic.oup.com
The discovery of myostatin and our introduction to the “Mighty Mouse” over a decade ago
spurred both basic and applied research and impacted popular culture as well. The …

Candidate growth genes in finfish—where should we be looking?

C De-Santis, DR Jerry - Aquaculture, 2007 - Elsevier
On the back of the genomics revolution significant investment has been made towards the
identification of candidate growth genes in livestock that can be used to speed up genetic …

Activin signaling as an emerging target for therapeutic interventions

K Tsuchida, M Nakatani, K Hitachi, A Uezumi… - Cell Communication and …, 2009 - Springer
After the initial discovery of activins as important regulators of reproduction, novel and
diverse roles have been unraveled for them. Activins are expressed in various tissues and …

Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects

JE Dominique, C Gérard - Experimental cell research, 2006 - Elsevier
Since its identification in 1997, myostatin has been considered as a novel and unique
negative regulator of muscle growth, as mstn−/− mice display a dramatic and widespread …

Zebrafish as a model organism for nutrition and growth: towards comparative studies of nutritional genomics applied to aquacultured fishes

PE Ulloa, P Iturra, R Neira, C Araneda - Reviews in Fish Biology and …, 2011 - Springer
Zebrafish (Danio rerio) is a common research model in fish studies of toxicology,
developmental biology, neurobiology and molecular genetics; it has been proposed as a …

The functional role of long non-coding RNA in myogenesis and skeletal muscle atrophy

K Hitachi, M Honda, K Tsuchida - Cells, 2022 - mdpi.com
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …