In this review, all papers relevant to the molecular genetics of bipolar disorder published
from 2004 to the present (mid 2006) are reviewed, and major results on depression are …

Bipolar disorder (BP) is a complex disorder caused by a number of liability genes interacting
with the environment. In recent years, a large number of linkage and association studies …

Autism is a heterogeneous condition that is likely to result from the combined effects of
multiple genetic factors interacting with environmental factors. Given its complexity, the study …

Bipolar disorder is a common, heritable mental illness characterized by recurrent episodes
of mania and depression. Despite considerable effort to elucidate the genetic underpinnings …

INTRODUCTION: Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is
hypothesized to play a role in the pathogenesis of bipolar disorder (BD). Conflicting results …

BACKGROUND: Age at onset of psychosis may carry clinical significance across psychotic
disorders and appears to be associated with specific genetic abnormalities. METHODS: We …

Tondo L, Lepri B, Cruz N, Baldessarini RJ. Age at onset in 3014 Sardinian bipolar and major
depressive disorder patients. Objective: To test if onset age in major affective illnesses is …

I review and evaluate genetic and genomic evidence salient to the hypothesis that the
development and evolution of psychotic spectrum conditions have been mediated in part by …

The interaction between polarity at onset (PAO) and age at onset (AAO) appears to be
important for interpreting results of previous analyses of AAO in bipolar disorder (BD). Using …

Objectives Existing and previously published datasets were examined for associations
between illness and treatment characteristics and monocyte pro‐inflammatory gene …