Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Polyketides are an important class of structurally diverse natural products derived from a
precursor molecule consisting of a chain of alternating ketone and methylene groups. These …

Abstract A novel ethyl 3-amino-2-cyano-6-hydroxy-7, 12-dioxo-2, 7, 12, 12a-tetrahydro-1H-
benzo [g] pyrimido [1, 2-a] quinoline-5-carboxylate (3ABPQC) was synthesized by treating …

Background: Naphthoquinones are a class of aromatic compounds relevant for their
chemical characteristics, structural properties, and biological activity. These compounds are …

To develop novel chemotherapeutic alternatives for the treatment of Chagas disease, in this
study, a set of new amino naphthoquinone derivatives were synthesised and evaluated in …

In the present study, we designed and synthesized thiolated VK3 analogs (VK3a–g) along
with an extensive antimicrobial study. After the evaluation of the antibacterial and antifungal …

The medicinal potential of quinoline, a flexible bicyclic heterocyclic scaffold, is significant.
Some compounds with quinoline nuclei are preferred therapeutic agents for various …

Two subseries of aminated quinolinequinones (AQQs, AQQ1–16) containing electron-
withdrawing group (EWG) or electron-donating group (EDG) in aryl amine moiety were …

The supramolecular binding behavior of the fluorescent compound 4-(4-(dimethylamino)
phenyl)-1-methylpyridinium (APP+) and CB [7] was investigated in aqueous solution by …

In continuation our effort to research the chemical space of aryloxy-naphthoquinones as
potential anti-Chagas agents, we synthesized nine derivatives and these compounds were …