A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19
AS Lokhande, PV Devarajan - European Journal of Pharmacology, 2021 - Elsevier
The global pandemic of Coronavirus Disease 2019 (COVID-19) has brought the world to a
grinding halt. A major cause of concern is the respiratory distress associated mortality …
grinding halt. A major cause of concern is the respiratory distress associated mortality …
[HTML][HTML] A comprehensive review on pharmacologic agents, immunotherapies and supportive therapeutics for COVID-19
The emergence of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected many countries throughout …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected many countries throughout …
Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse
F Seehusen, JJ Clark, P Sharma, EG Bentley, A Kirby… - Viruses, 2022 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) not only affects the
respiratory tract but also causes neurological symptoms such as loss of smell and taste …
respiratory tract but also causes neurological symptoms such as loss of smell and taste …
Fast one-pot microwave-assisted green synthesis of highly fluorescent plant-inspired S, N-self-doped carbon quantum dots as a sensitive probe for the antiviral drug …
In this study, we report a one-pot, green, cost-efficient, and fast synthesis of plant-based
sulfur and nitrogen self-co-doped carbon quantum dots (S, N-CQDs). By 4-min microwave …
sulfur and nitrogen self-co-doped carbon quantum dots (S, N-CQDs). By 4-min microwave …
[HTML][HTML] Nitazoxanide superiority to placebo to treat moderate COVID-19–A Pilot prove of concept randomized double-blind clinical trial.
VF Blum, S Cimerman, JR Hunter, P Tierno… - …, 2021 - thelancet.com
Background The absence of specific antivirals to treat COVID-19 leads to the repositioning
of candidates' drugs. Nitazoxanide (NTZ) has a broad antiviral effect. Methods This was a …
of candidates' drugs. Nitazoxanide (NTZ) has a broad antiviral effect. Methods This was a …
Broad‐spectrum prodrugs with anti‐SARS‐CoV‐2 activities: Strategies, benefits, and challenges
Z Wang, L Yang - Journal of medical virology, 2022 - Wiley Online Library
In this era, broad‐spectrum prodrugs with anti‐severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) activities are gaining considerable attention owing to their …
coronavirus 2 (SARS‐CoV‐2) activities are gaining considerable attention owing to their …
Synergistic and antagonistic drug combinations against SARS-CoV-2
Antiviral drug development for coronavirus disease 2019 (COVID-19) is occurring at an
unprecedented pace, yet there are still limited therapeutic options for treating this disease …
unprecedented pace, yet there are still limited therapeutic options for treating this disease …
Therapeutic potential of nitazoxanide: an appropriate choice for repurposing versus SARS-CoV-2?
AV Stachulski, J Taujanskas, SL Pate… - ACS infectious …, 2020 - ACS Publications
The rapidly growing COVID-19 pandemic is the most serious global health crisis since the
“Spanish flu” of 1918. There is currently no proven effective drug treatment or prophylaxis for …
“Spanish flu” of 1918. There is currently no proven effective drug treatment or prophylaxis for …
Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2
The spread of new coronavirus infection starting December 2019 as novel SARS-CoV-2,
identified as the causing agent of COVID-19, has affected all over the world and been …
identified as the causing agent of COVID-19, has affected all over the world and been …
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm …
N Chandiwana, C Kruger, H Johnstone… - …, 2022 - thelancet.com
Background This exploratory study investigated four repurposed anti-infective drug
regimens in outpatients with COVID-19. Methods This phase 2, single centre, randomised …
regimens in outpatients with COVID-19. Methods This phase 2, single centre, randomised …