Continuous renal replacement therapy: who, when, why, and how

S Tandukar, PM Palevsky - Chest, 2019 - Elsevier
Continuous renal replacement therapy (CRRT) is commonly used to provide renal support
for critically ill patients with acute kidney injury, particularly patients who are …

Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients

RP Veiga, JA Paiva - Critical Care, 2018 - Springer
Antimicrobials are among the most important and commonly prescribed drugs in the
management of critically ill patients and beta-lactams are the most common antibiotic class …

Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

F Pea, P Viale, M Furlanut - Clinical pharmacokinetics, 2005 - Springer
Antimicrobials are among the most important and commonly prescribed drugs in the
management of critically ill patients. Selecting the appropriate antimicrobial at the …

Principles of antibacterial dosing in continuous renal replacement therapy

G Choi, CD Gomersall, Q Tian, GM Joynt… - Critical care …, 2009 - journals.lww.com
Objectives: To outline the concepts involved in optimizing antibacterial dosing in critically ill
patients with acute renal failure undergoing continuous renal replacement therapy (CRRT) …

A guide to understanding antimicrobial drug dosing in critically ill patients on renal replacement therapy

V Pistolesi, S Morabito, F Di Mario… - Antimicrobial agents …, 2019 - Am Soc Microbiol
ABSTRACT A careful management of antimicrobials is essential in the critically ill with acute
kidney injury, especially if renal replacement therapy is required. Acute kidney injury may …

Pharmacokinetics/pharmacodynamics of antibacterials in the Intensive Care Unit: setting appropriate dosing regimens

F Scaglione, L Paraboni - International journal of antimicrobial agents, 2008 - Elsevier
Patients admitted to Intensive Care Units (ICUs) are at very high risk of developing severe
nosocomial infections. Consequently, antimicrobials are among the most important and …

Technology Insight: treatment of renal failure in the intensive care unit with extended dialysis

D Fliser, JT Kielstein - Nature clinical practice Nephrology, 2006 - nature.com
Sustained low-efficiency dialysis (SLED) is an increasingly popular extracorporeal renal
replacement therapy for patients with renal failure in the intensive care unit (ICU). Several …

Drug dosing in continuous renal replacement therapy: general rules

M Schetz - Current opinion in critical care, 2007 - journals.lww.com
Drug dosing in continuous renal replacement therapy: general... : Current Opinion in Critical
Care Drug dosing in continuous renal replacement therapy: general rules : Current Opinion in …

Antibiotic dosing in critically ill patients with acute kidney injury

RF Eyler, BA Mueller - Nature Reviews Nephrology, 2011 - nature.com
A common cause of acute kidney injury (AKI) is sepsis, which makes appropriate dosing of
antibiotics in these patients essential. Drug dosing in critically ill patients with AKI, however …

Principles of antibacterial dosing in continuous renal replacement therapy

G Choi, CD Gomersall, Q Tian, GM Joynt, AMMY Li… - Blood purification, 2010 - karger.com
Background: Appropriate antibacterial therapy is important to maximize patient survival in
sepsis. Acute renal failure complicates optimal antibiotic administration. Methods: MEDLINE …