This review summarizes our current understanding of translation in prokaryotes, focusing on
the mechanistic and structural aspects of each phase of translation: initiation, elongation …

Translation initiation is a crucial step of protein synthesis which largely defines how the
composition of the cellular transcriptome is converted to the proteome and controls the …

RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …

Deciphering physiological changes that mediate transition of Mycobacterium tuberculosis
between replicating and nonreplicating states is essential to understanding how the …

Individual Streptomyces species have the genetic potential to produce a diverse array of
natural products of commercial, medical and veterinary interest. However, these products …

In this study, we evaluated how gene expression differs in mature Pseudomonas aeruginosa
biofilms as opposed to planktonic cells by the use of RNA sequencing technology that gives …

Corynebacterium glutamicum is an important industrial organism that is widely used in the
production of amino acids, nucleotides and vitamins. To extend its product spectrum and …

Background The initiating nucleotide found at the 5'end of primary transcripts has a
distinctive triphosphorylated end that distinguishes these transcripts from all other RNA …

Translation efficiency has been mainly studied by ribosome profiling, which only provides an
incomplete picture of translation kinetics. Here, we integrated the absolute quantifications of …

Caulobacter crescentus undergoes an asymmetric cell division controlled by a genetic
circuit that cycles in space and time. We provide a universal strategy for defining the coding …