[HTML][HTML] Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy

S Motyka, K Jafernik, H Ekiert, J Sharifi-Rad… - Biomedicine & …, 2023 - Elsevier
The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …

Podophyllotoxin: history, recent advances and future prospects

Z Shah, UF Gohar, I Jamshed, A Mushtaq, H Mukhtar… - Biomolecules, 2021 - mdpi.com
Podophyllotoxin, along with its various derivatives and congeners are widely recognized as
broad-spectrum pharmacologically active compounds. Etoposide, for instance, is the …

[图书][B] Anticancer agents from natural products

GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

[HTML][HTML] Recent progress of research on herbal products used in traditional Chinese medicine: the herbs belonging to the divine Husbandman's herbal foundation …

KH Lee, S Morris-Natschke, K Qian, Y Dong… - Journal of Traditional …, 2012 - Elsevier
This article will review selected herbal products from Chinese Materia Medica that are used
in Traditional Chinese Medicine. The herbs come from the upper, middle, and lower class …

Isolation and identification of an endophytic strain of Fusarium oxysporum producing podophyllotoxin from Juniperus recurva

A Kour, AS Shawl, S Rehman, P Sultan… - World Journal of …, 2008 - Springer
Podophyllotoxin, a well-known naturally occurring aryltetralin lignan occurs in few plant
species that is used as a precursor for the chemical synthesis of the anticancer drugs like …

Effect of free and microencapsulated thyme essential oil on quality attributes of minimally processed lettuce

GE Viacava, JF Ayala-Zavala… - Postharvest Biology and …, 2018 - Elsevier
In the present study, thyme essential oil (TO) was used as a natural antioxidant and
antimicrobial agent to enhance the quality and shelf-life of minimally processed lettuce …

Podophyllotoxin: Current approaches to its biotechnological production and future challenges

M Yousefzadi, M Sharifi, M Behmanesh… - Engineering in Life …, 2010 - Wiley Online Library
Many plant‐derived agents are being used to treat cancer, including taxol, vinblastine,
vincristine, or camptothecin and podophyllotoxin derivatives, among others. Plant …

Isolation of fatty acids with anticancer activity fromProtaetia brevitarsis Larva

YC Yoo, BH Shin, JH Hong, J Lee, HY Chee… - Archives of pharmacal …, 2007 - Springer
In this study, biologically active compounds were isolated from Protaetia brevitarsis larva
(PBL) by dichloromethane extraction. The dichloromethane extract from PBL was highly …

Drug discovery and development with plant-derived compounds

O Potterat, M Hamburger - Natural Compounds as Drugs Volume I, 2008 - Springer
An overview is given on current efforts in drug development based on plant-derived natural
products. Emphasis is on projects which have advanced to clinical development …

Fungal elicitors for enhanced production of secondary metabolites in plant cell suspension cultures

A Baldi, AK Srivastava, VS Bisaria - Symbiotic fungi: principles and …, 2009 - Springer
Biotechnological production of plant-based secondary metabolites by a cell culture-based
bioprocess generally suffers from an inherent disadvantage of low yield. In order to …