The biology of peroxisome proliferator activated receptors (PPARs) in physiological and
pathophysiological processes has been primarily studied in peripherial organs and tissues …

Agonists of the peroxisome proliferator activated receptor gamma (PPARγ) are currently
used for treatment of type 2 diabetes due to their insulin sensitizing and glucose metabolism …

The peroxisome proliferator-activated receptor-g (PPAR-γ) belongs to a large group of
nuclear receptors controlling reproduction, metabolism, development and immune …

Peroxisome proliferator‐activated receptor gamma (PPARγ), a member of the nuclear
receptor superfamily, is activated by several compounds, including the thiazolidinediones. In …

Mitochondrial impairment is increasingly implicated in the etiology of toxicity caused by
some thiazolidinediones, fibrates, and statins. We examined the effects of members of these …

Thiazolidinedione (TZD) class of peroxisome proliferator receptor gamma (PPAR-γ) agonists
display neuroprotective effects in experimental Parkinson's disease (PD) models. Neurons …

Some polyunsaturated fatty acids (PUFAs), if not all, have been shown to have tumoricidal
action, but their exact mechanism (s) of action is not clear. In the present study, we observed …

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with an
extremely poor prognosis. There is a dire need to develop effective therapeutics to …

Peroxisome proliferator-activated receptor gamma (PPARγ) agonists demonstrate antitumor
activity likely through transactivating genes that regulate cell proliferation, apoptosis, and …

Multiple genetic, metabolic, and environmental abnormalities are known to contribute to the
pathogenesis of Alzheimer's dementia (AD). If all of those abnormalities were addressed it …