Mass spectrometry-based proteomic technology and its application to study skeletal muscle cell biology
Voluntary striated muscles are characterized by a highly complex and dynamic proteome
that efficiently adapts to changed physiological demands or alters considerably during …
that efficiently adapts to changed physiological demands or alters considerably during …
Spatial proteomics for the molecular characterization of breast cancer
Breast cancer (BC) is a major global health issue, affecting a significant proportion of the
female population and contributing to high rates of mortality. One of the primary challenges …
female population and contributing to high rates of mortality. One of the primary challenges …
Integrative AI-driven strategies for advancing precision medicine in infectious diseases and beyond: a novel multidisciplinary approach
RH Allami, MG Yousif - arXiv preprint arXiv:2307.15228, 2023 - arxiv.org
Precision medicine, tailored to individual patients based on their genetics, environment, and
lifestyle, shows promise in managing complex diseases like infections. Integrating artificial …
lifestyle, shows promise in managing complex diseases like infections. Integrating artificial …
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial
RI Gallagher, J Wulfkuhle, DM Wolf… - Cell Reports …, 2023 - cell.com
Molecular subtyping of breast cancer is based mostly on HR/HER2 and gene expression-
based immune, DNA repair deficiency, and luminal signatures. We extend this description …
based immune, DNA repair deficiency, and luminal signatures. We extend this description …
Mapping cancer biology in space: applications and perspectives on spatial omics for oncology
Technologies to decipher cellular biology, such as bulk sequencing technologies and single-
cell sequencing technologies, have greatly assisted novel findings in tumor biology. Recent …
cell sequencing technologies, have greatly assisted novel findings in tumor biology. Recent …
Microbial pathogenesis in the era of spatial omics
S Lempke, D May, SE Ewald - Infection and Immunity, 2023 - Am Soc Microbiol
The biology of a cell, whether it is a unicellular organism or part of a multicellular network, is
influenced by cell type, temporal changes in cell state, and the cell's environment. Spatial …
influenced by cell type, temporal changes in cell state, and the cell's environment. Spatial …
A comparison of tissue dissection techniques for diagnostic, prognostic, and theragnostic analysis of human disease
EM Walsh, MK Halushka - Pathobiology, 2023 - karger.com
Histopathology has historically been the critical technique for the diagnosis and treatment of
human disease. Today, genomics, transcriptomics, and proteomics from specific cells, rather …
human disease. Today, genomics, transcriptomics, and proteomics from specific cells, rather …
Spatiotemporal Omics-Refining the landscape of precision medicine
Current streamline of precision medicine uses histomorphological and molecular
information to indicate individual phenotypes and genotypes to achieve optimal outcome of …
information to indicate individual phenotypes and genotypes to achieve optimal outcome of …
Laser capture microdissection: a gear for pancreatic cancer research
BH Rao, P Souček, V Hlaváč - International Journal of Molecular Sciences, 2022 - mdpi.com
The advancement in molecular techniques has been attributed to the quality and
significance of cancer research. Pancreatic cancer (PC) is one of the rare cancers with …
significance of cancer research. Pancreatic cancer (PC) is one of the rare cancers with …
Advancements in oncoproteomics technologies: Treading toward translation into clinical practice
Proteomics continues to forge significant strides in the discovery of essential biological
processes, uncovering valuable information on the identity, global protein abundance …
processes, uncovering valuable information on the identity, global protein abundance …