Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …
interest in recent years owing to their ability to replace natural enzymes in various …
Metal toxicity links to Alzheimer's disease and neuroinflammation
As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …
disease (AD) and the associated socio-economic burden are predicted to worsen. While …
Superoxide dismutases and superoxide reductases
Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …
A cerium vanadate nanozyme with specific superoxide dismutase activity regulates mitochondrial function and ATP synthesis in neuronal cells
N Singh, SK NaveenKumar… - Angewandte Chemie …, 2021 - Wiley Online Library
Nanoparticles that functionally mimic the activity of metal‐containing enzymes (metallo‐
nanozymes) are of therapeutic importance for treating various diseases. However, it is still …
nanozymes) are of therapeutic importance for treating various diseases. However, it is still …
Luminescent chemodosimeters for bioimaging
Y Yang, Q Zhao, W Feng, F Li - Chemical Reviews, 2013 - ACS Publications
Luminescence bioimaging offers a unique approach for visualizing morphological details of
tissues with subcellular resolution and has become a powerful tool for the manipulation and …
tissues with subcellular resolution and has become a powerful tool for the manipulation and …
Metal coordination in photoluminescent sensing
Coordination chemistry plays an essential role in the design of photoluminescent probes for
metal ions. Metal coordination to organic dyes induces distinct optical responses which …
metal ions. Metal coordination to organic dyes induces distinct optical responses which …
Mutant SOD1 mediated pathogenesis of amyotrophic lateral sclerosis
SJ Kaur, SR McKeown, S Rashid - Gene, 2016 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neural disorder that causes death of the motor
neurons in the brain and spinal cord; this affects the voluntary muscles and gradually leads …
neurons in the brain and spinal cord; this affects the voluntary muscles and gradually leads …
Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options
Free radicals are common outcome of normal aerobic cellular metabolism. In-built
antioxidant system of body plays its decisive role in prevention of any loss due to free …
antioxidant system of body plays its decisive role in prevention of any loss due to free …
[HTML][HTML] Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
The causes of amyotrophic lateral sclerosis (ALS), a devastating human neurodegenerative
disease, are poorly understood, although the protein TDP-43 has been suggested to have a …
disease, are poorly understood, although the protein TDP-43 has been suggested to have a …
[HTML][HTML] Oxidative stress and human health
Redox degenerative reactions of the biological system inevitably produce reactive oxygen
species (ROS) and their derivatives. Oxidative stress is the result of an imbalance in pro …
species (ROS) and their derivatives. Oxidative stress is the result of an imbalance in pro …