Brucellosis vaccines: past, present and future

GG Schurig, N Sriranganathan, MJ Corbel - Veterinary microbiology, 2002 - Elsevier
The first effective Brucella vaccine was based on live Brucella abortus strain 19, a laboratory-
derived strain attenuated by an unknown process during subculture. This induces …

Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans

J Ko, GA Splitter - Clinical microbiology reviews, 2003 - Am Soc Microbiol
Brucellosis caused by Brucella spp. is a major zoonotic disease. Control of brucellosis in
agricultural animals is a prerequisite for the prevention of this disease in human beings …

Recent advancement, immune responses, and mechanism of action of various vaccines against intracellular bacterial infections

A Ali, A Waris, MA Khan, M Asim, AU Khan, S Khan… - Life Sciences, 2023 - Elsevier
Emerging and re-emerging bacterial infections are a serious threat to human and animal
health. Extracellular bacteria are free-living, while facultative intracellular bacteria replicate …

The yersiniabactin transport system is critical for the pathogenesis of bubonic and pneumonic plague

JD Fetherston, O Kirillina, AG Bobrov… - Infection and …, 2010 - Am Soc Microbiol
Iron acquisition from the host is an important step in the pathogenic process. While Yersinia
pestis has multiple iron transporters, the yersiniabactin (Ybt) siderophore-dependent system …

Intranasal Immunization with Recombinant Lactococcus lactis Secreting Murine Interleukin-12 Enhances Antigen-Specific Th1 Cytokine Production

LG Bermúdez-Humarán, P Langella… - Infection and …, 2003 - Am Soc Microbiol
ABSTRACT Interleukin-12 (IL-12), a heterodimeric cytokine, plays an important role in
cellular immunity to several bacterial, viral, and parasitic infections and has adjuvant activity …

Protective live oral brucellosis vaccines stimulate Th1 and Th17 cell responses

B Clapp, JA Skyberg, X Yang, T Thornburg… - Infection and …, 2011 - Am Soc Microbiol
Zoonotic transmission of brucellosis often results from exposure to Brucella-infected
livestock, feral animals, or wildlife or frequently via consumption of unpasteurized milk …

[图书][B] The prokaryotes: Vol. 5: proteobacteria: alpha and beta subclasses

M Dworkin - 2006 - books.google.com
The revised Third Edition of The Prokaryotes, acclaimed as a classic reference in the field,
offers new and updated articles by experts from around the world on taxa of relevance to …

Production of the Type IV Secretion System Differs among Brucella Species as Revealed with VirB5- and VirB8-Specific Antisera

B Rouot, MT Alvarez-Martinez, C Marius… - Infection and …, 2003 - Am Soc Microbiol
Expression of the virB operon, encoding the type IV secretion system required for Brucella
suis virulence, occurred in the acidic phagocytic vacuoles of macrophages and could be …

[PDF][PDF] Cytokine response and clinicopathological findings in Brucella infected camels (Camelus dromedarius)

M El-Boshy, H Abbas, S El-Khodery… - Veterinarni …, 2009 - agriculturejournals.cz
The present study had the aim of assessing the cytokine response and selected
clinicopathological findings associated with brucellosis in camels (Camelus dromedarius) …

Intact Purine Biosynthesis Pathways Are Required for Wild-Type Virulence of Brucella abortus 2308 in the BALB/c Mouse Model

RB Alcantara, RDA Read, MW Valderas… - Infection and …, 2004 - Am Soc Microbiol
Brucella abortus 2308 derivatives with mini-Tn 5 insertions in purE, purL, and purD display
significant attenuation in the BALB/c mouse model, while isogenic mutants with mini-Tn 5 …