MHC class II epitope predictive algorithms
Major histocompatibility complex class II (MHC‐II) molecules sample peptides from the
extracellular space, allowing the immune system to detect the presence of foreign microbes …
extracellular space, allowing the immune system to detect the presence of foreign microbes …
Major histocompatibility complex linked databases and prediction tools for designing vaccines
Presently, the major histocompatibility complex (MHC) is receiving considerable interest
owing to its remarkable role in antigen presentation and vaccine design. The specific …
owing to its remarkable role in antigen presentation and vaccine design. The specific …
Genome based screening of epitope ensemble vaccine candidates against dreadful visceral leishmaniasis using immunoinformatics approach
Visceral leishmaniasis (VL) is a dreadful protozoan disease caused by Leishmania
donovani that severely affects huge populations in tropical and sub-tropical regions. The …
donovani that severely affects huge populations in tropical and sub-tropical regions. The …
pDOCK: a new technique for rapid and accurate docking of peptide ligands to Major Histocompatibility Complexes
JM Khan, S Ranganathan - Immunome Research, 2010 - Springer
Background Identification of antigenic peptide epitopes is an essential prerequisite in T cell-
based molecular vaccine design. Computational (sequence-based and structure-based) …
based molecular vaccine design. Computational (sequence-based and structure-based) …
Limitations of Ab Initio Predictions of Peptide Binding to MHC Class II Molecules
Successful predictions of peptide MHC binding typically require a large set of binding data
for the specific MHC molecule that is examined. Structure based prediction methods promise …
for the specific MHC molecule that is examined. Structure based prediction methods promise …
PAAQD: Predicting immunogenicity of MHC class I binding peptides using amino acid pairwise contact potentials and quantum topological molecular similarity …
T Saethang, O Hirose, I Kimkong, VA Tran… - Journal of …, 2013 - Elsevier
Prediction of peptide immunogenicity is a promising approach for novel vaccine discovery.
Conventionally, epitope prediction methods have been developed to accelerate the process …
Conventionally, epitope prediction methods have been developed to accelerate the process …
MHC class II binding prediction by molecular docking
M Atanasova, I Dimitrov, DR Flower… - Molecular …, 2011 - Wiley Online Library
Abstract Proteins of the Major Histocompatibility Complex (MHC) bind self and nonself
peptide antigens or epitopes within the cell and present them at the cell surface for …
peptide antigens or epitopes within the cell and present them at the cell surface for …
EpicCapo: epitope prediction using combined information of amino acid pairwise contact potentials and HLA-peptide contact site information
Background Epitope identification is an essential step toward synthetic vaccine development
since epitopes play an important role in activating immune response. Classical experimental …
since epitopes play an important role in activating immune response. Classical experimental …
[HTML][HTML] Prediction of MHC binding peptide using Gibbs motif sampler, weight matrix and artificial neural network
The identification of MHC restricted epitopes is an important goal in peptide based vaccine
and diagnostic development. As wet lab experiments for identification of MHC binding …
and diagnostic development. As wet lab experiments for identification of MHC binding …
[PDF][PDF] PREDICTION OF PEPTIDE BINDING TO SWINE LEUKOCYTE ANTIGEN (SLA-1) PROTEINS BY MOLECULAR DOCKING
Swine influenza is a highly contagious viral infection in pigs causing an acute upper
respiratory disease. The control of swine influenza by vaccination has become more difficult …
respiratory disease. The control of swine influenza by vaccination has become more difficult …