Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …
tissue and cell functions and significant increases in the risks of various aging-related …
Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer
Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …
NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps
JM Adrover, SAC McDowell, XY He, DF Quail… - Cancer Cell, 2023 - cell.com
Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …
not only in the eradication of pathogens but also in cancer initiation and progression …
TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models
J Wu, Z Feng, L Chen, Y Li, H Bian, J Geng… - Nature …, 2022 - nature.com
Ferroptosis is a nonapoptotic cell death process that requires cellular iron and the
accumulation of lipid peroxides. In progressive rheumatoid arthritis (RA), synovial fibroblasts …
accumulation of lipid peroxides. In progressive rheumatoid arthritis (RA), synovial fibroblasts …
Oxidative stress in cardiovascular diseases: still a therapeutic target?
T Senoner, W Dichtl - Nutrients, 2019 - mdpi.com
Cardiovascular diseases (CVD) are complex entities with heterogenous pathophysiologic
mechanisms and increased oxidative stress has been viewed as one of the potential …
mechanisms and increased oxidative stress has been viewed as one of the potential …
ROS generation and antioxidant defense systems in normal and malignant cells
AV Snezhkina, AV Kudryavtseva… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …
in many cellular compartments and play a major role in signaling pathways. Overproduction …
The role of oxidative stress in physiopathology and pharmacological treatment with pro‐and antioxidant properties in chronic diseases
A García-Sánchez, AG Miranda-Díaz… - Oxidative Medicine …, 2020 - Wiley Online Library
Oxidative stress (OS) has the ability to damage different molecules and cellular structures,
altering the correct function of organs and systems. OS accumulates in the body by …
altering the correct function of organs and systems. OS accumulates in the body by …
Oxidative stress and cancer
JE Klaunig - Current pharmaceutical design, 2018 - ingentaconnect.com
Background: Cancer is considered a major cause of death worldwide. The etiology of cancer
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …
Mechanistic basis of antimicrobial actions of silver nanoparticles
TC Dakal, A Kumar, RS Majumdar… - Frontiers in microbiology, 2016 - frontiersin.org
Multidrug resistance of the pathogenic microorganisms to the antimicrobial drugs has
become a major impediment toward successful diagnosis and management of infectious …
become a major impediment toward successful diagnosis and management of infectious …
The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles
A Abdal Dayem, MK Hossain, SB Lee, K Kim… - International journal of …, 2017 - mdpi.com
Nanoparticles (NPs) possess unique physical and chemical properties that make them
appropriate for various applications. The structural alteration of metallic NPs leads to …
appropriate for various applications. The structural alteration of metallic NPs leads to …