The disorders known as bone marrow failure syndromes (BMFS) are life-threatening
disorders characterized by absence of one or more hematopoietic lineages in the peripheral …

α1-microglobulin (A1M) is a small protein present in vertebrates including humans. It has
several physiologically relevant properties, including binding of heme and radicals as well …

Diamond-Blackfan anemia (DBA) is a congenital erythroblastopenia that is characterized by
a blockade in erythroid differentiation related to impaired ribosome biogenesis. DBA …

Although the individual structures and respiratory functions of cytochromes are well studied,
the structural basis for their assembly, including transport of heme for attachment, are …

Pain is necessary to alert us to actual or potential tissue damage. Specialized nerve cells in
the body periphery, so called nociceptors, are fundamental to mediate pain perception and …

Heme is an iron-containing prosthetic group necessary for the function of several proteins
termed" hemoproteins." Erythrocytes contain most of the body's heme in the form of …

Background Runs of homozygosity (ROH) are continuous homozygous regions typically
located in the DNA sequence of diploid organisms. Identifications of ROH that lead to …

Large White pigs are extensively utilized in China for their remarkable characteristics of
rapid growth and the high proportion of lean meat. The economic traits of pigs, comprising …

Feline leukemia virus subgroup C receptor 1 (FLVCR1) has been reported to have a crucial
role in variety of biological processes, including cell proliferation, cell death, apoptosis …

Introduction: Diamond Blackfan anemia (DBA) is a rare congenital disease characterized by
defective maturation of the erythroid progenitors in the bone marrow, for which treatment …