Charged-particle therapy in cancer: clinical uses and future perspectives

M Durante, R Orecchia, JS Loeffler - Nature Reviews Clinical Oncology, 2017 - nature.com
Radiotherapy with high-energy charged particles has become an attractive therapeutic
option for patients with several tumour types because this approach better spares healthy …

[PDF][PDF] Delivering high-quality cancer care: charting a new course for a system in crisis

LA Levit, E Balogh, SJ Nass, P Ganz - 2013 - commed.vcu.edu
A cancer diagnosis is one of the most feared events. Rarely diagnosed before the late
twentieth century, cancer now competes with cardiovascular disease as the leading cause of …

Clinically localized prostate cancer: AUA/ASTRO guideline, part I: introduction, risk assessment, staging, and risk-based management

JA Eastham, GB Auffenberg, DA Barocas… - The Journal of …, 2022 - auajournals.org
Purpose: The summary presented herein represents Part I of the three-part series dedicated
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing risk assessment …

Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience

T Kamada, H Tsujii, EA Blakely, J Debus… - The Lancet …, 2015 - thelancet.com
Charged particle therapy is generally regarded as cutting-edge technology in oncology.
Many proton therapy centres are active in the USA, Europe, and Asia, but only a few centres …

Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Safety of combining radiotherapy with immune-checkpoint inhibition

WL Hwang, LRG Pike, TJ Royce, BA Mahal… - Nature reviews Clinical …, 2018 - nature.com
Immune-checkpoint inhibitors targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4),
programmed cell death protein 1 (PD-1), or programmed cell death 1 ligand 1 (PD-L1) have …

Second cancer risk after primary cancer treatment with three‐dimensional conformal, intensity‐modulated, or proton beam radiation therapy

M Xiang, DT Chang, EL Pollom - Cancer, 2020 - Wiley Online Library
Background The comparative risks of a second cancer diagnosis are uncertain after primary
cancer treatment with 3‐dimensional conformal radiotherapy (3DCRT), intensity‐modulated …

Charged particle therapy—optimization, challenges and future directions

JS Loeffler, M Durante - Nature reviews Clinical oncology, 2013 - nature.com
The use of charged particle therapy to control tumours non-invasively offers advantages
over conventional radiotherapy. Protons and heavy ions deposit energy far more selectively …

Prostate cancer, version 2.2014

JL Mohler, PW Kantoff, AJ Armstrong… - Journal of the National …, 2014 - jnccn.org
Prostate cancer has surpassed lung cancer as the most common cancer in men in the
United States. The NCCN Guidelines for Prostate Cancer provide multidisciplinary …

A systematic review of the cost and cost‐effectiveness studies of proton radiotherapy

V Verma, MV Mishra, MP Mehta - Cancer, 2016 - Wiley Online Library
BACKGROUND Economic analyses of new technologies, such as proton‐beam
radiotherapy (PBT), are a public health priority. To date, no systematic review of the cost …