The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

Controversy surrounds reports describing the derivation of human trophoblast cells from
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …

Introduction The placenta, a transient organ in humans, is essential for pregnancy
maintenance and fetal development. Trophoblast and stromal cells are the main cell types …

The amnion is the inner of two membranes surrounding the fetus. That it arises from
embryonic epiblast cells prior to gastrulation suggests that it may retain a reservoir of stem …

Trophoblast invasion of the uterine extracellular matrix, a critical process of human
implantation and essential for fetal development, is a striking example of controlled …

Background The aim of this study was to examine the invasiveness of first trimester
trophoblasts according to the secretion profile of MMP-2 and-9 at different gestational …

Implantation failure and inadequate placental development are important contributors to
infertility, recurrent miscarriage, and other pregnancy-related problems in women. Better …

During the first trimester of pregnancy the uterus is massively infiltrated by decidual natural
killer cells (dNK). These cells are not killers, but they rather provide a microenvironment that …

The human placenta represents an abundant; easily accessible and unlimited study material
(at birth a human placenta provides about 500g of trophoblast). Cytotrophoblastic cells …