Genome-wide molecular-profiling studies have revealed the characteristic genetic
alterations and epigenetic profiles associated with different types of gliomas. These …

Glioblastoma (WHO grade IV astrocytoma) is the most frequent primary brain tumor in adults,
representing a highly heterogeneous group of neoplasms that are among the most …

Background & Aims Next-generation sequencing (NGS) of pancreatic cyst fluid is a useful
adjunct in the assessment of patients with pancreatic cyst. However, previous studies have …

Background. Molecular profiling is revolutionizing cancer diagnostics and leading to
personalized therapeutic approaches. Herein we describe our clinical experience …

Background & Aims Intraductal oncocytic papillary neoplasms (IOPNs) of the pancreas and
bile duct contain epithelial cells with numerous, large mitochondria and are cystic precursors …

In the 5th edition of the WHO CNS tumor classification (CNS5, 2021), multiple molecular
characteristics became essential diagnostic criteria for many additional CNS tumor types …

Objective Despite improvements in imaging, serum CA19-9 and pathological evaluation,
differentiating between benign and malignant bile duct strictures remains a diagnostic …

Diffuse midline gliomas (including diffuse intrinsic pontine glioma, DIPG) are highly morbid
glial neoplasms of the thalamus or brainstem that typically arise in young children and are …

Current classification of gliomas is based on histological criteria according to the World
Health Organization (WHO) classification of tumors of the central nervous system. Over the …

Simple Summary Glioblastoma is the most common malignant primary brain tumor in adults.
Glioblastoma accounts for 2 to 3 cases per 100,000 persons in North America and Europe …