An important role of the immune system is in the surveillance for abnormal or transformed
cells, which is known as cancer immunosurveillance. Through this process, the first changes …

Abnormal activity of the core cell-cycle machinery is seen in essentially all tumor types and
represents a driving force of tumorigenesis. Recent studies revealed that cell-cycle proteins …

Proper progression throughout the cell division cycle depends on the expression level of a
family of proteins known as cyclins, and the subsequent activation of cyclin-dependent …

Cancer‐related gene expression programs are strongly influenced by posttranscriptional
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …

Although autoantibodies have been recognized as participants in pathogenesis of tissue
injury, the collateral role of autoantibodies as reporters from the immune system identifying …

Aberrant levels of the G2/M cyclin cyclin B1 (gene CCNB1) have been associated with
multiple cancers; however, the literature lacks a focused and comprehensive analysis of the …

MicroRNAs (miRs) are involved in the pathogenesis of several neoplasms; however, there
are no data on their expression patterns and possible roles in adrenocortical tumors. Our …

The question of whether human tumors express antigens that can be recognized by the
immune system has been answered with a resounding YES. Most were identified through …

Background Cyclin B1, the regulatory subunit of cyclin-dependent kinase 1 (Cdk1), is
essential for the transition from G2 phase to mitosis. Cyclin B1 is very often found to be …

Prevention or early detection is one of the most promising strategies against colorectal
cancer (CRC), the second leading cause of cancer death in the US. Recent studies indicate …