[HTML][HTML] Adipose tissue and insulin resistance in obese

B Ahmed, R Sultana, MW Greene - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

Challenges in the diagnosis of insulin resistance: focusing on the role of HOMA-IR and Tryglyceride/glucose index

DL Tahapary, LB Pratisthita, NA Fitri, C Marcella… - Diabetes & Metabolic …, 2022 - Elsevier
Abstract Background and aims Metabolic Syndrome (MS) prevalence is increasing
worldwide in line with the growing prevalence of obesity. The underlying mechanism of MS …

Association between insulin resistance and the development of cardiovascular disease

V Ormazabal, S Nair, O Elfeky, C Aguayo… - Cardiovascular …, 2018 - Springer
For many years, cardiovascular disease (CVD) has been the leading cause of death around
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Oxidative stress and diabetic complications

F Giacco, M Brownlee - Circulation research, 2010 - Am Heart Assoc
Oxidative stress plays a pivotal role in the development of diabetes complications, both
microvascular and cardiovascular. The metabolic abnormalities of diabetes cause …

A clinical perspective of obesity, metabolic syndrome and cardiovascular disease

TS Han, MEJ Lean - JRSM cardiovascular disease, 2016 - journals.sagepub.com
The metabolic syndrome is a condition characterized by a special constellation of reversible
major risk factors for cardiovascular disease and type 2 diabetes. The main, diagnostic …

Metabolic syndrome—a new world‐wide definition. A consensus statement from the international diabetes federation

KGMM Alberti, P Zimmet, J Shaw - Diabetic medicine, 2006 - Wiley Online Library
Aims To establish a unified working diagnostic tool for the metabolic syndrome (MetS) that is
convenient to use in clinical practice and that can be used world‐wide so that data from …

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

M Matsuda, RA DeFronzo - Diabetes care, 1999 - Am Diabetes Assoc
OBJECTIVE: Several methods have been proposed to evaluate insulin sensitivity from the
data obtained from the oral glucose tolerance test (OGTT). However, the validity of these …

Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

ES Ford, WH Giles, WH Dietz - Jama, 2002 - jamanetwork.com
ContextThe Third Report of the National Cholesterol Education Program Expert Panel on
Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) highlights …

In vivo ROS production and use of oxidative stress-derived biomarkers to detect the onset of diseases such as Alzheimer's disease, Parkinson's disease, and …

A Umeno, V Biju, Y Yoshida - Free radical research, 2017 - Taylor & Francis
Breakthroughs in biochemistry have furthered our understanding of the onset and
progression of various diseases, and have advanced the development of new therapeutics …