Critical enzyme reactions in aromatic catabolism for microbial lignin conversion

E Erickson, A Bleem, E Kuatsjah, AZ Werner… - Nature Catalysis, 2022 - nature.com
The application of microbes to valorize aromatic compounds derived from the abundant
plant biopolymer lignin is a rapidly developing area of research that may ultimately enable …

[HTML][HTML] Flavoprotein monooxygenases: versatile biocatalysts

CE Paul, D Eggerichs, AH Westphal, D Tischler… - Biotechnology …, 2021 - Elsevier
Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …

Gut microbiome of mealworms (Tenebrio molitor Larvae) show similar responses to polystyrene and corn straw diets

T Mamtimin, H Han, A Khan, P Feng, Q Zhang, X Ma… - Microbiome, 2023 - Springer
Background Some insects can degrade both natural and synthetic plastic polymers, their
host and gut microbes play crucial roles in this process. However, there is still a scientific …

Enzymatic Hydroxylations of sp3-Carbons

J Munch, P Pullmann, W Zhang, MJ Weissenborn - Acs Catalysis, 2021 - ACS Publications
Enzymatic hydroxylation of activated and nonactivated sp3-carbons attracts keen interest
from the chemistry community as it is one of the most challenging tasks in organic synthesis …

Unifying and versatile features of flavin-dependent monooxygenases: Diverse catalysis by a common C4a-(hydro) peroxyflavin

A Phintha, P Chaiyen - Journal of Biological Chemistry, 2023 - ASBMB
Flavin-dependent monooxygenases (FDMOs) are known for their remarkable versatility and
for their crucial roles in various biological processes and applications. Extensive research …

Microbial degradation of halogenated aromatics: molecular mechanisms and enzymatic reactions

P Pimviriyakul, T Wongnate, R Tinikul… - Microbial …, 2020 - Wiley Online Library
Halogenated aromatics are used widely in various industrial, agricultural and household
applications. However, due to their stability, most of these compounds persist for a long time …

Non-Native Site-Selective Enzyme Catalysis

D Mondal, HM Snodgrass, CA Gomez… - Chemical …, 2023 - ACS Publications
The ability to site-selectively modify equivalent functional groups in a molecule has the
potential to streamline syntheses and increase product yields by lowering step counts …

Reductive Dehalogenation of Herbicides Catalyzed by Pd0NPs in a H2-Based Membrane Catalyst-Film Reactor

Y Cai, YH Luo, X Long, MA Roldan… - Environmental …, 2022 - ACS Publications
More food production required to feed humans will require intensive use of herbicides to
protect against weeds. The widespread application and persistence of herbicides pose …

Flavin‐N5OOH Functions as both a Powerful Nucleophile and a Base in the Superfamily of Flavoenzymes

Q Zhang, Q Chen, S Shaik… - Angewandte Chemie …, 2024 - Wiley Online Library
Flavoenzymes can mediate a large variety of oxidation reactions through the activation of
oxygen. However, the O2 activation chemistry of flavin enzymes is not yet fully exploited …

Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and …

J Kratky, D Eggerichs, T Heine… - Angewandte Chemie …, 2023 - Wiley Online Library
Flavoprotein monooxygenases are a versatile group of enzymes for biocatalytic
transformations. Among these, group E monooxygenases (GEMs) catalyze enantioselective …