Redefining fundamental concepts of transcription initiation in bacteria

C Mejía-Almonte, SJW Busby, JT Wade… - Nature Reviews …, 2020 - nature.com
Despite enormous progress in understanding the fundamentals of bacterial gene regulation,
our knowledge remains limited when compared with the number of bacterial genomes and …

Pathogenesis of Helicobacter pylori infection

V Camilo, T Sugiyama, E Touati - Helicobacter, 2017 - Wiley Online Library
Helicobacter pylori is responsible for the most commonly found infection in the world's
population. It is the major risk factor for gastric cancer development. Numerous studies …

[HTML][HTML] Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing

D Pohl, PM Keller, V Bordier… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is highly prevalent in the human population and may
lead to severe gastrointestinal pathology including gastric and duodenal ulcers, mucosa …

Pathogenesis of Helicobacter pylori infection

LA Waskito, NR Salama, Y Yamaoka - Helicobacter, 2018 - Wiley Online Library
In this review, we highlight progress in the last year in characterizing known virulence factors
like flagella and the Cag type IV secretion system with sophisticated structural and …

Helicobacter pylori: molecular basis for colonization and survival in gastric environment and resistance to antibiotics. A short review

S Fagoonee, R Pellicano - Infectious Diseases, 2019 - Taylor & Francis
Helicobacter pylori is a human-specific pathogen with a strict tropism for the gastric mucosa.
This bacterium infects around half of the world population and is the main responsible for …

A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment

R Kinoshita-Daitoku, K Kiga, M Miyakoshi… - Nature …, 2021 - nature.com
Long-term infection of the stomach with Helicobacter pylori can cause gastric cancer.
However, the mechanisms by which the bacteria adapt to the stomach environment are …

[HTML][HTML] The role of solute binding proteins in signal transduction

MA Matilla, Á Ortega, T Krell - Computational and Structural Biotechnology …, 2021 - Elsevier
The solute binding proteins (SBPs) of prokaryotes are present in the extracytosolic space.
Although their primary function is providing substrates to transporters, SBPs also stimulate …

[PDF][PDF] A repeat-associated small RNA controls the major virulence factors of Helicobacter pylori

SK Eisenbart, M Alzheimer, SR Pernitzsch, S Dietrich… - Molecular Cell, 2020 - cell.com
Many bacterial pathogens regulate their virulence genes via phase variation, whereby
length-variable simple sequence repeats control the transcription or coding potential of …

[HTML][HTML] Battle for metals: regulatory RNAs at the front line

M Charbonnier, G González-Espinoza… - Frontiers in Cellular …, 2022 - frontiersin.org
Metal such as iron, zinc, manganese, and nickel are essential elements for bacteria. These
nutrients are required in crucial structural and catalytic roles in biological processes …

Targeting of regulators as a promising approach in the search for novel antimicrobial agents

D Roncarati, V Scarlato, A Vannini - Microorganisms, 2022 - mdpi.com
Since the discovery of penicillin in the first half of the last century, antibiotics have become
the pillars of modern medicine for fighting bacterial infections. However, pathogens resistant …