[HTML][HTML] Integrating the neurodevelopmental and dopamine hypotheses of schizophrenia and the role of cortical excitation-inhibition balance
OD Howes, E Shatalina - Biological psychiatry, 2022 - Elsevier
The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …
[HTML][HTML] Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes
OD Howes, C Cummings, GE Chapman… - …, 2023 - nature.com
Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …
[HTML][HTML] Diagnosis of schizophrenia based on the data of various modalities: biomarkers and machine learning techniques
MG Sharaev, IK Malashenkova… - Современные …, 2022 - cyberleninka.ru
Schizophrenia is a socially significant mental disorder resulting frequently in severe forms of
disability. Diagnosis, choice of treatment tactics, and rehabilitation in clinical psychiatry are …
disability. Diagnosis, choice of treatment tactics, and rehabilitation in clinical psychiatry are …
Virtual brain twins: from basic neuroscience to clinical use
Virtual brain twins are personalized, generative and adaptive brain models based on data
from an individual's brain for scientific and clinical use. After a description of the key …
from an individual's brain for scientific and clinical use. After a description of the key …
Gyrification across psychotic disorders: A bipolar-schizophrenia network of intermediate phenotypes study
Background The profiles of cortical gyrification across schizophrenia, bipolar I disorder, and
schizoaffective disorder have been studied to a limited extent, report discordant findings …
schizoaffective disorder have been studied to a limited extent, report discordant findings …
Ricci flow-based brain surface covariance descriptors for diagnosing Alzheimer's disease
Automated feature extraction from MRI brain scans and diagnosis of Alzheimer's disease are
ongoing challenges. With advances in 3D imaging technology, 3D data acquisition is …
ongoing challenges. With advances in 3D imaging technology, 3D data acquisition is …
The Contribution of Explainable Machine Learning Algorithms Using ROI-based Brain Surface Morphology Parameters in Distinguishing Early-onset Schizophrenia …
Rationale and Objectives To differentiate early-onset schizophrenia (EOS) from early-onset
bipolar disorder (EBD) using surface-based morphometry measurements and brain volumes …
bipolar disorder (EBD) using surface-based morphometry measurements and brain volumes …
Orbitofrontal cortex hypergyrification in hallucinating schizophrenia patients: surface ratio as a promising brain biomarker
C Núñez, C Stephan-Otto, A Roldán, EM Grasa… - medRxiv, 2024 - medrxiv.org
Background: There has been increasing interest in the study of brain gyrification in
schizophrenia since it may provide additional useful information on the cytoarchitecture and …
schizophrenia since it may provide additional useful information on the cytoarchitecture and …
Ricci flow-based brain surface covariance descriptors for Alzheimer disease
Automated feature extraction from MRI brain scans and diagnosis of Alzheimer's disease are
ongoing challenges. With advances in 3D imaging technology, 3D data acquisition is …
ongoing challenges. With advances in 3D imaging technology, 3D data acquisition is …
Landscape of Intrinsically Disordered Proteins in Mental Disorder Diseases
X Zhang, Y Yang, G Hu, R Liu, N Zhou, X Song… - 2024 - preprints.org
Abstract Intrinsically Disordered Proteins (IDPs) play crucial roles in signal transduction, cell
differentiation, and transcriptional regulation. Many disrupted genes associated with mental …
differentiation, and transcriptional regulation. Many disrupted genes associated with mental …