Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives

S Shen, C Zhan, C Yang, AR Fernie, J Luo - Molecular Plant, 2023 - cell.com
Plants are natural experts in organic synthesis, being able to generate large numbers of
specific metabolites with widely varying structures that help them adapt to variable survival …

Current insights into the microbial degradation of nicosulfuron: Strains, metabolic pathways, and molecular mechanisms

J Zhong, S Wu, WJ Chen, Y Huang, Q Lei, S Mishra… - Chemosphere, 2023 - Elsevier
Nicosulfuron is among the sulfonylurea herbicides that are widely used to control annual
and perennial grass weeds in cornfields. However, nicosulfuron residues in the environment …

Endogenous plant metabolites against insects

RWJ Kortbeek, M van der Gragt, PM Bleeker - European Journal of Plant …, 2019 - Springer
Herbivorous insects are responsible for large losses to agriculture through feeding damage
itself but also by vectoring pathogens such as viruses. Plants have evolved various …

Characterization of gossypol biosynthetic pathway

X Tian, JX Ruan, JQ Huang, CQ Yang… - Proceedings of the …, 2018 - National Acad Sciences
Gossypol and related sesquiterpene aldehydes in cotton function as defense compounds
but are antinutritional in cottonseed products. By transcriptome comparison and …

Using Synthetic Biology to Understand the Function of Plant Specialized Metabolites

Y Bai, X Liu, IT Baldwin - Annual Review of Plant Biology, 2024 - annualreviews.org
Plant specialized metabolites (PSMs) are variably distributed across taxa, tissues, and
ecological contexts; this variability has inspired many theories about PSM function, which to …

Exploiting natural variation in tomato to define pathway structure and metabolic regulation of fruit polyphenolics in the lycopersicum complex

T Tohge, F Scossa, R Wendenburg, P Frasse, I Balbo… - Molecular plant, 2020 - cell.com
While the structures of plant primary metabolic pathways are generally well defined and
highly conserved across species, those defining specialized metabolism are less well …

Tomato root specialized metabolites evolved through gene duplication and regulatory divergence within a biosynthetic gene cluster

RE Kerwin, JE Hart, PD Fiesel, YR Lou, P Fan… - Science …, 2024 - science.org
Tremendous plant metabolic diversity arises from phylogenetically restricted specialized
metabolic pathways. Specialized metabolites are synthesized in dedicated cells or tissues …

Tip of the trichome: evolution of acylsugar metabolic diversity in Solanaceae

P Fan, BJ Leong, RL Last - Current Opinion in Plant Biology, 2019 - Elsevier
Highlights•Solanaceae glandular trichomes produce structurally diverse insecticidal
acylsugars.•Diversity is achieved by enzyme promiscuity and core metabolic enzyme …

Natural variation in wild tomato trichomes; selecting metabolites that contribute to insect resistance using a random forest approach

RWJ Kortbeek, MD Galland, A Muras… - BMC plant biology, 2021 - Springer
Background Plant-produced specialised metabolites are a powerful part of a plant's first line
of defence against herbivorous insects, bacteria and fungi. Wild ancestors of present-day …

Mapping of specialized metabolite terms onto a plant phylogeny using text mining and large language models

L Busta, D Hall, B Johnson, M Schaut… - The Plant …, 2024 - Wiley Online Library
Plants produce a staggering array of chemicals that are the basis for organismal function
and important human nutrients and medicines. However, it is poorly defined how these …