Biochemistry and molecular biology of flaviviruses

NJ Barrows, RK Campos, KC Liao, KR Prasanth… - Chemical …, 2018 - ACS Publications
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

Pathogenesis and virulence of flavivirus infections

SW van Leur, T Heunis, D Munnur, S Sanyal - Virulence, 2021 - Taylor & Francis
The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

[HTML][HTML] Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions

RA Flynn, JA Belk, Y Qi, Y Yasumoto, J Wei… - Cell, 2021 - cell.com
SARS-CoV-2 is the cause of a pandemic with growing global mortality. Using
comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) …

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection

W Kamel, M Noerenberg, B Cerikan, H Chen… - Molecular cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …

The multiples fates of the flavivirus RNA genome during pathogenesis

C Mazeaud, W Freppel, L Chatel-Chaix - Frontiers in genetics, 2018 - frontiersin.org
The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow
fever viruses) which constitute important public health concerns worldwide. For several of …

Molecular insights into the flavivirus replication complex

K Van den Elsen, JP Quek, D Luo - Viruses, 2021 - mdpi.com
Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral
pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever …

Discovery of widespread host protein interactions with the pre-replicated genome of CHIKV using VIR-CLASP

B Kim, S Arcos, K Rothamel, J Jian, KL Rose… - Molecular Cell, 2020 - cell.com
The primary interactions between incoming viral RNA genomes and host proteins are crucial
to infection and immunity. Until now, the ability to study these events was lacking. We …

A global interactome map of the dengue virus NS1 identifies virus restriction and dependency host factors

ML Hafirassou, L Meertens, C Umaña-Diaz, A Labeau… - Cell reports, 2017 - cell.com
Dengue virus (DENV) infections cause the most prevalent mosquito-borne viral disease
worldwide, for which no therapies are available. DENV encodes seven non-structural (NS) …

An RNA-centric dissection of host complexes controlling flavivirus infection

YS Ooi, K Majzoub, RA Flynn, MA Mata, J Diep… - Nature …, 2019 - nature.com
Flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), cause severe human
disease. Co-opting cellular factors for viral translation and viral genome replication at the …

Host cytoskeletal vimentin serves as a structural organizer and an RNA-binding protein regulator to facilitate Zika viral replication

Y Zhang, S Zhao, Y Li, F Feng, M Li… - Proceedings of the …, 2022 - National Acad Sciences
Emerging microbe infections, such as Zika virus (ZIKV), pose an increasing threat to human
health. Investigations on ZIKV replication have revealed the construction of replication …