Targeting the ANGPT–TIE2 pathway in malignancy

H Huang, A Bhat, G Woodnutt, R Lappe - Nature Reviews Cancer, 2010 - nature.com
Angiopoietins (ANGPTs) are ligands of the endothelial cell receptor TIE2 and have crucial
roles in the tumour angiogenic switch. Increased expression of ANGPT2 relative to ANGPT1 …

Gastric exocrine and endocrine secretion

ML Schubert - Current opinion in gastroenterology, 2009 - journals.lww.com
Despite our vast knowledge, the understanding of the regulation of gastric acid secretion in
health and disease is far from complete. A better understanding of the pathways and …

Apical recycling of the gastric parietal cell H, K-ATPase

JG Forte, L Zhu - Annual review of physiology, 2010 - annualreviews.org
The gastric parietal cell was the first system where a regulated membrane recycling
hypothesis was proposed as the principal means for moving molecular transporters between …

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions

C Xiao, SA Ogle, MA Schumacher… - American Journal …, 2010 - journals.physiology.org
In the stomach, strictly regulated cell adherens junctions are crucial in determining epithelial
cell differentiation. Sonic Hedgehog (Shh) regulates epithelial cell differentiation in the adult …

Phospho-regulated ACAP4-Ezrin interaction is essential for histamine-stimulated parietal cell secretion

X Ding, H Deng, D Wang, J Zhou, Y Huang… - Journal of Biological …, 2010 - ASBMB
The ezrin-radixin-moesin proteins provide a regulated linkage between membrane proteins
and the cortical cytoskeleton and also participate in signal transduction pathways. Ezrin is …

The spatiotemporal matching pattern of Ezrin/Periaxin involved in myoblast differentiation and fusion and Charcot-Marie-Tooth disease-associated muscle atrophy

R Zhang, X Bao, Y Liu, Y Wang, XY Li, G Tan… - Journal of Translational …, 2023 - Springer
Abstract Background Clinically, Charcot-Marie-Tooth disease (CMT)-associated muscle
atrophy still lacks effective treatment. Deletion and mutation of L-periaxin can be involved in …

Expression of moesin and CD 44 is associated with poor prognosis in gastric adenocarcinoma

WY Jung, Y Kang, H Lee, YJ Mok, HK Kim… - …, 2013 - Wiley Online Library
Aims CD 44 has been reported as a negative prognostic marker in gastric cancer. It interacts
with moesin in epithelial–mesenchymal transition. To date, to our knowledge, there has …

[PDF][PDF] Self-renewal of the gastric epithelium from stem and progenitor cells

W Hoffmann - Front Biosci (Schol Ed), 2013 - article.imrpress.com
[Frontiers in Bioscience, Scholar, 5, 720-731, January 1, 2013] 720 Self-renewal of the gastric
epithelium from stem and progeni Page 1 [Frontiers in Bioscience, Scholar, 5, 720-731 …

Acid secretion-associated translocation of KCNJ15 in gastric parietal cells

W He, W Liu, CS Chew, SS Baker… - American Journal …, 2011 - journals.physiology.org
Potassium ions are required for gastric acid secretion. Several potassium channels have
been implicated in providing K+ at the apical membrane of parietal cells. In examining the …

Immediate and late effects of early weaning on rat gastric cell differentiation

M Teles Silva, K Mesquita da Silva… - International Journal of …, 2019 - mdpi.com
Background: Gastric glands grow and cells reach differentiation at weaning in rats. By
considering that early weaning (EW) can affect the timing of development, we aimed to …