[HTML][HTML] Molecular docking, drug-likeness and DFT study of some modified tetrahydrocurcumins as potential anticancer agents

A Mahal, M Al-Janabi, V Eyüpoğlu, A Alkhouri… - Saudi Pharmaceutical …, 2024 - Elsevier
The present study utilized molecular docking and density functional theory (DFT)
approaches, and ADMET (absorption, distribution, metabolism, excretion, and toxicity) …

Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs

S Wan, F Wu, JC Rech, ME Green… - Journal of the …, 2011 - ACS Publications
The potent cytotoxins pederin and psymberin have been prepared through concise synthetic
routes (10 and 14 steps in the longest linear sequences, respectively) that proceed via a late …

Synthesis, anticancer activity, and molecular docking of New 1, 2, 3-Triazole linked tetrahydrocurcumin derivatives

M Duan, A Mahal, A Alkouri, C Wang, Z Zhang, J Ren… - Molecules, 2024 - mdpi.com
Cancer is one of the deadliest diseases to humanity. There is significant progress in treating
this disease, but developing some drugs that can fight this disease remains a challenge in …

Green synthesis and antimicrobial activity of copper nanoparticles (Cu-NPS) by Piper longum fruit extract

A Mahal, E Mahal, S Al-Mutlaq, AH Daham… - Bulletin of the Chemical …, 2024 - ajol.info
Many applications of green synthesis in the field of environment and biomedicine aiming at
decreasing the use of toxic chemicals through utilizing of plants which are safe. In this study …

Synthesis and applications of tricarbonylmethane compounds

KP Reber, HE Burdge - Organic Preparations and Procedures …, 2018 - Taylor & Francis
Organic compounds containing the tricarbonylmethane functional group occupy a unique
place in organic chemistry (Figure 1). As C-acylated derivatives of the more familiar 1, 3 …

Cycloaddition reactions of allenylphosphonates and related allenes with dialkyl acetylenedicarboxylates, 1, 3-diphenylisobenzofuran, and anthracene

KV Sajna, R Kotikalapudi, M Chakravarty… - The Journal of …, 2011 - ACS Publications
Cycloaddition reactions of allenylphosphonates [(RO) 2P (O)[(R1) C C CR22] with dialkyl
acetylenedicarboxylates, 1, 3-diphenylisobenzofuran, and anthracene have been …

Synthesis of novel quinolines with antibacterial activity

DS Zinad, A Mahal, GA Salman… - Organic Preparations …, 2024 - Taylor & Francis
In recent years, the development of pharmaceuticals and high-value fine chemicals based
on heterocycles has sustained strong activity. 1-12 Discovery of new medicines based on …

Synthesis of substituted 2-amino oxazoles with their cobalt (II) and platinum (IV) complexes and evaluation of their biological activity

AZ Husain, YS Al-Jawaheri, AY Al-Assafe - Bulletin of the Chemical Society …, 2024 - ajol.info
Many applications of green synthesis in the field of environment and biomedicine aiming at
decreasing the use of toxic chemicals through utilizing of plants which are safe. In this study …

Synthesis of Fluorinated Arenes and Hetarenes Based on One-Pot Cyclizations of 1, 3-Bis (trimethylsilyloxy)-1, 3-butadienes

P Langer - Synlett, 2009 - thieme-connect.com
Thieme E-Journals - Synlett / Full Text DE EN Home Products Journals Books Book Series
Service Library Service Help Contact Portal SYNLETT Full-text search Full-text search Author …

Regioselective synthesis of 4-acyl-1-hydroxy-2, 3-benzodioates by chelation-controlled [3+ 3] annulation of 3-acyl-4-ethoxy-2-oxo-3-enoates with 1, 3-bis …

A Riahi, M Shkoor, O Fatunsin, RA Khera… - Organic & …, 2009 - pubs.rsc.org
Regioselective synthesis of 4-acyl-1-hydroxy-2,3-benzodioates by chelation-controlled [3+3]
annulation of 3-acyl-4-ethoxy-2-oxo-3-enoates with 1,3-bis ... - Organic & Biomolecular …