Current state of potential mechanisms supporting low intensity focused ultrasound for neuromodulation

J Dell'Italia, JL Sanguinetti, MM Monti… - Frontiers in human …, 2022 - frontiersin.org
Low intensity focused ultrasound (LIFU) has been gaining traction as a non-invasive
neuromodulation technology due to its superior spatial specificity relative to transcranial …

Non-invasive transcranial brain modulation for neurological disorders treatment: a narrative review

EA Mosilhy, EE Alshial, MM Eltaras, MMA Rahman… - Life Sciences, 2022 - Elsevier
Noninvasive brain stimulation/modulation is a rapidly emerging technique that has been
implemented in different clinical applications. The commonly noninvasive techniques used …

Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation

K Yu, X Niu, E Krook-Magnuson, B He - Nature communications, 2021 - nature.com
Transcranial focused ultrasound (tFUS) is a promising neuromodulation technique, but its
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …

Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation

F Li, J Gallego, NN Tirko, J Greaser, D Bashe… - Nature …, 2024 - nature.com
Microglia are important players in surveillance and repair of the brain. Implanting an
electrode into the cortex activates microglia, produces an inflammatory cascade, triggers the …

Transcranial focused ultrasound neuromodulation: a review of the excitatory and inhibitory effects on brain activity in human and animals

T Zhang, N Pan, Y Wang, C Liu, S Hu - Frontiers in Human …, 2021 - frontiersin.org
Non-invasive neuromodulation technology is important for the treatment of brain diseases.
The effects of focused ultrasound on neuronal activity have been investigated since the …

Ultrasound neuromodulation: Mechanisms and the potential of multimodal stimulation for neuronal function assessment

HAS Kamimura, A Conti, N Toschi… - Frontiers in physics, 2020 - frontiersin.org
Focused ultrasound (FUS) neuromodulation has shown that mechanical waves can interact
with cell membranes and mechanosensitive ion channels, causing changes in neuronal …

[HTML][HTML] Transcranial focused ultrasound stimulation with high spatial resolution

S Kim, Y Jo, G Kook, C Pasquinelli, H Kim, K Kim… - Brain Stimulation, 2021 - Elsevier
Background Low-intensity transcranial focused ultrasound stimulation is a promising
candidate for noninvasive brain stimulation and accurate targeting of brain circuits because …

Review of noninvasive or minimally invasive deep brain stimulation

X Liu, F Qiu, L Hou, X Wang - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Brain stimulation is a critical technique in neuroscience research and clinical application.
Traditional transcranial brain stimulation techniques, such as transcranial magnetic …

Weak ultrasound contributes to neuromodulatory effects in the rat motor cortex

PC Chu, CS Huang, PK Chang, RS Chen… - International Journal of …, 2023 - mdpi.com
Transcranial focused ultrasound (tFUS) is a novel neuromodulating technique. It has been
demonstrated that the neuromodulatory effects can be induced by weak ultrasound …

Effect of low intensity transcranial ultrasound stimulation on neuromodulation in animals and humans: an updated systematic review

T Kim, C Park, PY Chhatbar, J Feld… - Frontiers in …, 2021 - frontiersin.org
Background: Although low-intensity transcranial ultrasound stimulation (LI-TUS) has
received more recognition for its neuromodulation potential, there remains a crucial …