Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

Drug development suffers from a lack of predictive and human-relevant in vitro models.
Organ-on-chip (OOC) technology provides advanced culture capabilities to generate …

Organ-on-chip systems are promising new in vitro research tools in medical,
pharmaceutical, and biological research. Their main benefit, compared to standard cell …

Microphysiological systems (MPS, also known as “organ-on-a-chip”,“body-on-a-chip”, or
“human-on-a-chip”) have emerged over the last 15 years as attractive systems to probe …

Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …

Hepatology and drug development for liver diseases require in vitro liver models. Typical
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …

Over the last few years, the intestine has been extensively studied using in vitro microfluidic
systems, commonly known as gut-on-a-chip (GOC) devices. This interest has been due not …

Organ-on-a-chip devices have enabled major breakthroughs in biomedical research, but
they have yet to be successfully translated to the pharmaceutical industry. Traditional …

Digital light processing (DLP)‐based bioprinting technology has recently aroused
considerable concerns as a strategy to deliver biomedical materials and/or specific cells to …