Abstract Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem,
zopiclone, and zaleplon) are FDA-approved for insomnia disorders with a strong evidence …

This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Based on electrophysiological, neurochemical, genetic and neuropharmacological
approaches, it is currently accepted that serotonin (5-HT) functions predominantly to …

Sleep researchers in different disciplines disagree about how fully dreaming can be
explained in terms of brain physiology. Debate has focused on whether REM sleep …

Several theories claim that dreaming is a random by-product of REM sleep physiology and
that it does not serve any natural function. Phenomenal dream content, however, is not as …

The raphe nuclei are distributed near the midline of the brainstem along its entire rostro-
caudal extension. The serotonergic neurons are their main neuronal components, although …

This paper presents an overview of the current knowledge of the neurophysiology and
cellular pharmacology of sleep mechanisms. It is written from the perspective that recent …

For 50 years, serotonin has been in the centre of the search for the mechanisms and control
of sleep. Serotonergic neurotransmission is related to the behavioural state of the animal …

scribí la primera edición de Fisiología de la Conducta hace más de un cuarto de siglo.
Cuando lo hice no podía imaginarme que algún día estaría escribiendo la octava edición …

Based on electrophysiological, neurochemical and neuropharmacological approaches, it is
currently accepted that serotonin (5-HT) and dopamine (DA) function to promote waking (W) …