One of the most important achievements of bacteria is its capability to adapt to the changing
conditions of the environment. The competition for nutrients with other microorganisms …

Secondary metabolites are a reliable and very important source of medicinal compounds.
While these molecules have been mined extensively, genome sequencing has suggested …

Soil dwelling Streptomyces species are faced with large variations in carbon or nitrogen
sources, phosphate, oxygen, iron, sulfur, and other nutrients. These drastic changes in key …

The search for novel bioactive compounds to overcome resistance to current therapeutics
has become of utmost importance. Streptomyces spp. are one of the main sources of …

This minireview mainly aims at the study of S-adenosyl-l-methionine (SAM) production by
microbial fermentation. A brief introduction of the biological role and application of SAM was …

We report the discovery and functional characterization of a new bacterial tRNA species.
The tRNA-Asp-AUC, from a fast-growing desert streptomycete, decodes GAU codons. In the …

Different types of post-translational modifications are present in bacteria that play essential
roles in bacterial metabolism modulation. Nevertheless, limited information is available on …

Streptomyces species are best known for their ability to produce abundant secondary
metabolites with versatile bioactivities and industrial importance. These metabolites are …

The secondary metabolites produced by bacterial species serve many clinically useful
purposes, and Streptomyces have been an abundant source of such compounds. However …

Most biosynthetic gene clusters (BGCs) of Actinobacteria are either silent or expressed less
than the detectable level. The non-genetic approaches including biological interactions …