Glycogen synthase kinase 3 beta: can it be a target for oral cancer

R Mishra - Molecular cancer, 2010 - Springer
Despite progress in treatment approaches for oral cancer, there has been only modest
improvement in patient outcomes in the past three decades. The frequent treatment failure is …

Wnt signaling in gynecologic malignancies

A McMellen, ER Woodruff, BR Corr, BG Bitler… - International journal of …, 2020 - mdpi.com
Gynecologic malignancies, including ovarian cancer, endometrial cancer, and cervical
cancer, affect hundreds of thousands of women worldwide every year. Wnt signaling …

MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity

DK Barupal, PK Haldiya, G Wohlgemuth, T Kind… - BMC …, 2012 - Springer
Background Exposure to environmental tobacco smoke (ETS) leads to higher rates of
pulmonary diseases and infections in children. To study the biochemical changes that may …

Subjugation of TGFβ signaling by human papilloma virus in head and neck squamous cell carcinoma shifts DNA repair from homologous recombination to alternative …

Q Liu, L Ma, T Jones, L Palomero, MA Pujana… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: Following cytotoxic therapy, 70% of patients with human papillomavirus
(HPV)-positive oropharyngeal head and neck squamous cell carcinoma (HNSCC) are alive …

The role of signaling pathways in cervical cancer and molecular therapeutic targets

J Manzo-Merino, A Contreras-Paredes… - Archives of medical …, 2014 - Elsevier
Cervical cancer is a public health issue in developing countries. Although the Pap smear
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …

Molecular mechanisms of HPV induced carcinogenesis in head and neck

T Rampias, C Sasaki, A Psyrri - Oral oncology, 2014 - Elsevier
A growing subgroup of oropharyngeal cancers is initiated by infection with high-risk human
papillomaviruses (HPVs). In parallel to mounting epidemiological evidence, solid …

Expression profiling of cervical cancers in I ndian women at different stages to identify gene signatures during progression of the disease

A Thomas, U Mahantshetty, S Kannan… - Cancer …, 2013 - Wiley Online Library
Cervical cancer is the second most common cancer among women worldwide, with
developing countries accounting for> 80% of the disease burden. Although in the West …

Regulation of the Wnt/β-catenin signaling pathway by human papillomavirus E6 and E7 oncoproteins

JO Muñoz Bello, L Olmedo Nieva, A Contreras Paredes… - Viruses, 2015 - mdpi.com
Cell signaling pathways are the mechanisms by which cells transduce external stimuli,
which control the transcription of genes, to regulate diverse biological effects. In cancer …

Clinical significance and prognosis value of Wnt signaling pathway in cervical cancer

A Bahrami, M Hasanzadeh… - Journal of cellular …, 2017 - Wiley Online Library
Cervical cancer is among the most commonly diagnosed cancer in women, supporting the
need for identification of novel prognostic and predictive biomarkers to predict the risk of …

Inhibition of Wnt-β-catenin signaling by ICRT14 drug depends of post-transcriptional regulation by HOTAIR in human cervical cancer HeLa cells

S Trujano-Camacho, D Cantú-de León… - Frontiers in …, 2021 - frontiersin.org
Background In Cervical cancer (CC), in addition to HPV infection, the most relevant
alteration during CC initiation and progression is the aberrant activation of Wnt/β-catenin …