Reactivation of embryonic genetic programs in tissue regeneration and disease
H Fazilaty, K Basler - Nature Genetics, 2023 - nature.com
Embryonic genetic programs are reactivated in response to various types of tissue damage,
providing cell plasticity for tissue regeneration or disease progression. In acute conditions …
providing cell plasticity for tissue regeneration or disease progression. In acute conditions …
Transcription factors in fibroblast plasticity and CAF heterogeneity
R Melchionna, P Trono, A Di Carlo… - Journal of Experimental …, 2023 - Springer
In recent years, research focused on the multifaceted landscape and functions of cancer-
associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities …
associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities …
Dual role of Snail1 as transcriptional repressor and activator
AG de Herreros - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Snail1 transcriptional factor plays a key role in the control of epithelial to mesenchymal
transition, a process that remodels tumor cells increasing their invasion and chemo …
transition, a process that remodels tumor cells increasing their invasion and chemo …
PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients
JR Ferreres, A Vinyals, R Campos‐Martin… - Molecular …, 2024 - Wiley Online Library
Paired related homeobox 1 (PRRX1) is an inducer of epithelial‐to‐mesenchymal transition
(EMT) in different types of cancer cells. We detected low PRRX1 expression in nevus but …
(EMT) in different types of cancer cells. We detected low PRRX1 expression in nevus but …
[HTML][HTML] Expression of LOXL3, NES, and SNAI1 in Melanoma Genesis and Progression
Melanoma is the most severe type of skin cancer and among the most malignant neoplasms
in humans. With the growing incidence of melanoma, increased numbers of therapeutic …
in humans. With the growing incidence of melanoma, increased numbers of therapeutic …
Melanoma-associated fibroblasts in tumor-promotion flammation and antitumor immunity: novel mechanisms and potential immunotherapeutic strategies
Q Zhou, X Jin, Y Zhao, Y Wang, M Tao… - Human Molecular …, 2024 - academic.oup.com
Melanoma, renowned for its aggressive behavior and resistance to conventional treatments,
stands as a formidable challenge in the oncology landscape. The dynamic and complex …
stands as a formidable challenge in the oncology landscape. The dynamic and complex …
NIR Enhanced pH‐Responsive Microneedles for Synergetic Therapy of Melanoma
W Han, L Yu, Z Liu, C Wang, Q Zhang, Y Xu, H Li… - ChemMedChem - Wiley Online Library
Melanoma has emerged as a significant threat to human life and health. Microneedle (MN)‐
mediated transdermal drug delivery (TDD) has garnered attention in melanoma treatment for …
mediated transdermal drug delivery (TDD) has garnered attention in melanoma treatment for …