TLR2 and TLR4 mediated host immune responses in major infectious diseases: a review

S Mukherjee, S Karmakar, SPS Babu - Brazilian Journal of Infectious …, 2016 - SciELO Brasil
During the course of evolution, multicellular organisms have been orchestrated with an
efficient and versatile immune system to counteract diverse group of pathogenic organisms …

Natural products are a promising source for anthelmintic drug discovery

KLTD Jayawardene, EA Palombo, PR Boag - Biomolecules, 2021 - mdpi.com
Parasitic nematodes infect almost all forms of life. In the human context, parasites are one of
the major causative factors for physical and intellectual growth retardation in the developing …

In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs

A Choudhury, S Mukherjee - Journal of medical virology, 2020 - Wiley Online Library
Abstract Coronavirus disease‐2019 (COVID‐19) outbreak due to novel coronavirus or
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has come out as …

[HTML][HTML] Designing efficient multi-epitope peptide-based vaccine by targeting the antioxidant thioredoxin of bancroftian filarial parasite

S Gorai, NC Das, PSS Gupta, SK Panda… - Infection, Genetics and …, 2022 - Elsevier
Thioredoxin is a low molecular weight redox-active protein of filarial parasite that plays a
crucial role in downregulating the host immune response to prolong the survival of the …

Reverse vaccinology assisted design of a novel multi-epitope vaccine to target Wuchereria bancrofti cystatin: An immunoinformatics approach

NC Das, PSS Gupta, SK Panda, MK Rana… - International …, 2023 - Elsevier
Proteases are the critical mediators of immunomodulation exerted by the filarial parasites to
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …

Graphene oxide dispersed supramolecular hydrogel capped benign green silver nanoparticles for anticancer, antimicrobial, cell attachment and intracellular imaging …

D Ghosh, S Dhibar, A Dey, S Mukherjee… - Journal of Molecular …, 2019 - Elsevier
Graphene oxide (GO) nanosheets dispersed a supramolecular hydrogel network
(GOSHGel) has been achieved. The microstructures of GO dispersed hydrogels are …

In-silico evidences on filarial cystatin as a putative ligand of human TLR4

NC Das, PS Sen Gupta, S Biswal, R Patra… - Journal of …, 2022 - Taylor & Francis
Cystatin is a small molecular weight immunomodulatory protein of filarial parasite that plays
a pivotal role in downregulating the host immune response to prolong the survival of the …

Phenolics and terpenoids; the promising new search for anthelmintics: a critical review

N Mukherjee, S Mukherjee, P Saini… - Mini reviews in …, 2016 - ingentaconnect.com
Ailments caused by helminth parasites are global causing different types of clinical
complications with permanent and long term morbidity in humans. Although huge advances …

A Novel Ligand of Toll-like Receptor 4 From the Sheath of Wuchereria bancrofti Microfilaria Induces Proinflammatory Response in Macrophages

S Mukherjee, S Mukherjee, TK Maiti… - The Journal of …, 2017 - academic.oup.com
Background. Lymphatic filariasis, frequently caused from Wuchereria bancrofti infection, is
endemic in several parts of the globe and responsible for human health problems and …

Designing of a chimeric multiepitope vaccine against bancroftian lymphatic filariasis through immunoinformatics approaches

R Parvin, M Habib Ullah Masum, J Ferdous… - Plos one, 2024 - journals.plos.org
The filarial worms of Wuchereria bancrofti are the primary cause of lymphatic filariasis (LF), a
mosquito-borne disease among the neglected tropical parasitic diseases. Considering the …