Mononuclear phagocyte plasticity includes the expression of functions related to the
resolution of inflammation, tissue repair and remodelling, particularly when these cells are …

It has been 10 years since the role of a chemokine receptor, CXCR4, in breast cancer
metastasis was first documented. Since then, the field of chemokines and cancer has grown …

Rationale: Recent studies indicate that tumor-associated macrophages (MΦ) with an M2
phenotype can influence cancer progression and metastasis, but the regulatory pathways …

Among heterogeneous primary tumors of the central nervous system (CNS), gliomas are the
most frequent type, with glioblastoma multiforme (GBM) characterized with the worst …

Chemokines are key players of the cancer-related inflammation. Chemokine ligands and
receptors are downstream of genetic events that cause neoplastic transformation and are …

Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer
function of lymphocytes—mainly NK cells, T cells and dendritic cells. Its increased levels in …

Glioma is the most common primary intracranial tumor and has the greatest prevalence of all
brain tumors. Treatment resistance and tumor recurrence in GBM are mostly explained by …

Simple Summary Chemokine signaling is crucial for tumorigenesis, proliferation,
angiogenesis, tumor progression and metastasis in glioblastoma. Furthermore, chemokines …

Recent studies highlight the importance of baseline functional immunity for immune
checkpoint blockade therapies. High‐dimensional systemic immune profiling is performed in …

The 1990s brought a burst of information regarding the structure, expression pattern, and
role in leukocyte migration and adhesion of chemokines and their receptors. At that time, the …