In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

As of November 2021, several SARS‐CoV‐2 variants appeared and became dominant
epidemic strains in many countries, including five variants of concern (VOCs) Alpha, Beta …

Epidemiologic surveillance has revealed decoupling of Coronavirus Disease 2019 (COVID-
19) hospitalizations and deaths from case counts after emergence of the Omicron (B. 1.1 …

Background Estimates of immunity and severity for the SARS-CoV-2 omicron subvariant BA.
5 are important to assess the public health impact associated with its rapid global spread …

The heterogeneity of the SARS-CoV-2 immune responses has become considerably more
complex over time and diverse immune imprinting is observed in vaccinated individuals …

ABSTRACT Background The Omicron (B. 1.1. 529) variant of SARS-CoV-2 has rapidly
achieved global dissemination, accounting for most infections in the United States by …

Introduction A precise estimate of the frequency and severity of SARS‐CoV‐2 reinfections
would be critical to optimize restriction and vaccination policies for the hundreds of millions …

Objectives To compare severity and clinical outcomes from Omicron as compared with the
Delta variant and to compare outcomes between Omicron sublineages. Methods We …

Abstract Background Although the SARS-CoV-2 Omicron variant is considered to induce
less severe disease, there have been no consistent results on the extent of the decrease in …

We present an interim analysis of a registered clinical study (NCT04800133) to establish
immunobridging with various antibody and cellular immunity markers and to compare the …