Carcinoma cells that are induced to suppress their epithelial features and upregulate
mesenchymal gene expression programs acquire traits that promote an invasive and …

Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …

Tumor metastasis is a multistep process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. Metastasis occurs through a series of steps …

Breast cancer is composed of multiple subtypes with distinct morphologies and clinical
implications. The advent of microarrays has led to a new paradigm in deciphering breast …

Breast carcinomas are often infiltrated by inflammatory cells, particularly macrophages and T
lymphocytes, but the significance of these cells remains unclear. One possible role of these …

Triple negative breast cancer (TNBC) is a molecularly heterogeneous disease whose
incidence is disproportionately higher in African American (AA) women compared to …

Breast cancer is a heterogeneous disease, comprising multiple entities associated with
distinctive histological and biological features, clinical presentations and behaviours and …

BACKGROUND. Triple‐negative breast cancer (estrogen receptor‐negative, progesterone
receptor‐negative, and HER2‐negative) is a high risk breast cancer that lacks the benefit of …

The current model of human breast cancer progression proposes a linear multi‐step process
which initiates as flat epithelial atypia (FEA), progresses to atypical ductal hyperplasia …

Recent gene expression profiling of breast cancer has identified specific subtypes with
clinical, biologic, and therapeutic implications. The basal-like group of tumors is …