Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

Simple Summary Neutrophils are a type of white blood cell that also play a role in cancer.
They have been shown to influence various aspects of the disease, including resistance to …

Simple Summary Proteolytic enzymes, such as matrix metalloproteinases, plasminogen
activators and cathepsins, as well as non-proteolytic enzymatic partners, such as …

Neutrophils are the principal trouper of the innate immune system. Activated neutrophils
undergo a noble cell death termed NETosis and release a mesh-like structure called …

Neutrophils are the key cells of our innate immune system mediating host defense via a
range of effector functions including phagocytosis, degranulation, and NETosis. For this …

Neutrophil Extracellular Traps (NETs) are a key form of pro-inflammatory cell death of
neutrophils characterized by the extrusion of extracellular webs of DNA containing …

Cancer is considered a major public health concern worldwide and is characterized by an
uncontrolled division of abnormal cells. The human immune system recognizes cancerous …

The extracellular matrix (ECM) is a highly dynamic and complex network structure, which
exists in almost all tissues and is the microenvironment that cells rely on for survival. ECM …

Preclinical models of cancer have long been paramount to understanding tumor
development and advancing the treatment of cancer. Creating preclinical models that mimic …

Extracellular DNA may serve as marker in liquid biopsies to determine individual diagnosis
and prognosis in cancer patients. Cell death or active release from various cell types …