Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Nanomedicines have evolved into various forms including dendrimers, nanocrystals,
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …

Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

The poor oral bioavailability arising from poor aqueous solubility should make drug research
and development more difficult. Various approaches have been developed with a focus on …

Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …

To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …

Nanosizing is one of the most important drug delivery platform approaches for the
commercial development of poorly soluble drug molecules. The research efforts of many …

The application of nanotechnology in areas of drug delivery and therapy (ie,
nanotherapeutics) is envisioned to have a great impact on public health. The ability of …

The characterization and performance of stable amorphous solid dispersion systems were
evaluated in 40 research papers reporting active pharmaceutical ingredient (API) dissolution …

Preformulation measurements are used to estimate the fraction absorbed in vivo for orally
administered compounds and thereby allow an early evaluation of the need for enabling …