The cholestatic liver injury could occur in response to a variety of diseases or xenobiotics.
Although cholestasis primarily affects liver function, it has been well-known that other organs …

Lead (Pb) is a highly toxic heavy metal widely dispersed in the environment because of
human industrial activities. Many studies revealed that Pb could adversely affect several …

Cholestasis is a significant decrease in bile flow. The liver is the primary organ affected by
cholestasis. Chronic cholestasis could entail to tissue fibrotic changes and liver cirrhosis …

Cholestasis is a multifaceted clinical complication. Obstructive jaundice induced by bile duct
ligation (BDL) is known as an animal model to investigate cholestasis and its associated …

Cyclosporine is an established medication for the prevention of transplant rejection.
However, adverse consequences such as nephrotoxicity, hepatotoxicity, and cholestasis …

Taurine (TAU) is the most abundant free amino acid in the human body. High concentrations
of this amino acid are found in tissues such as the skeletal muscle, brain, and kidney …

Cholestatic liver disease is a clinical complication with a wide range of etiologies. The liver
is the primary organ influenced by cholestasis. Other organs, rather than the liver (eg …

Cholestasis is a disorder of bile secretion and excretion caused by a variety of etiologies. At
present, there is a lack of functional foods or drugs that can be used for intervention …

Cholestasis is a clinical complication with different etiologies. The liver is the primary organ
influenced in cholestasis. Renal injury is also a severe clinical complication in …

Introduction: Cholestasis is the stoppage of bile flow, leading to the accumulation of
potentially cytotoxic bile components in the liver. These cytotoxic molecules affect many …