Mechanisms of mitochondrial iron-sulfur protein biogenesis
R Lill, SA Freibert - Annual review of biochemistry, 2020 - annualreviews.org
Mitochondria are essential in most eukaryotes and are involved in numerous biological
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …
Iron–sulfur cluster biogenesis and trafficking in mitochondria
JJ Braymer, R Lill - Journal of Biological Chemistry, 2017 - ASBMB
The biogenesis of iron–sulfur (Fe/S) proteins in eukaryotes is a multistage,
multicompartment process that is essential for a broad range of cellular functions, including …
multicompartment process that is essential for a broad range of cellular functions, including …
Biogenesis of iron–sulfur clusters and their role in DNA metabolism
R Shi, W Hou, ZQ Wang, X Xu - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Iron–sulfur (Fe/S) clusters (ISCs) are redox-active protein cofactors that their synthesis,
transfer, and insertion into target proteins require many components. Mitochondrial ISC …
transfer, and insertion into target proteins require many components. Mitochondrial ISC …
How do J-proteins get Hsp70 to do so many different things?
EA Craig, J Marszalek - Trends in biochemical sciences, 2017 - cell.com
Hsp70 chaperone machineries have pivotal roles in an array of fundamental biological
processes through their facilitation of protein folding, disaggregation, and remodeling. The …
processes through their facilitation of protein folding, disaggregation, and remodeling. The …
The role of mitochondria and the CIA machinery in the maturation of cytosolic and nuclear iron–sulfur proteins
R Lill, R Dutkiewicz, SA Freibert, T Heidenreich… - European journal of cell …, 2015 - Elsevier
Mitochondria have been derived from alpha-bacterial endosymbionts during the evolution of
eukaryotes. Numerous bacterial functions have been maintained inside the organelles …
eukaryotes. Numerous bacterial functions have been maintained inside the organelles …
Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions
SA Cory, JG Van Vranken… - Proceedings of the …, 2017 - National Acad Sciences
In eukaryotes, sulfur is mobilized for incorporation into multiple biosynthetic pathways by a
cysteine desulfurase complex that consists of a catalytic subunit (NFS1), LYR protein …
cysteine desulfurase complex that consists of a catalytic subunit (NFS1), LYR protein …
Establishment of strigolactone-producing bacterium-yeast consortium
Strigolactones (SLs) are a class of phytohormones playing diverse roles in plant growth and
development, yet the limited access to SLs is largely impeding SL-based foundational …
development, yet the limited access to SLs is largely impeding SL-based foundational …
Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
SA Freibert, AV Goldberg, C Hacker, S Molik… - Nature …, 2017 - nature.com
Microsporidians are obligate intracellular parasites that have minimized their genome
content and sub-cellular structures by reductive evolution. Here, we demonstrate that cristae …
content and sub-cellular structures by reductive evolution. Here, we demonstrate that cristae …
Unraveling the genetic basis of xylose consumption in engineered Saccharomyces cerevisiae strains
The development of biocatalysts capable of fermenting xylose, a five-carbon sugar abundant
in lignocellulosic biomass, is a key step to achieve a viable production of second-generation …
in lignocellulosic biomass, is a key step to achieve a viable production of second-generation …
Iron–sulfur proteins in plant mitochondria: roles and maturation
J Przybyla-Toscano, L Christ, O Keech… - Journal of …, 2021 - academic.oup.com
Abstract Iron–sulfur (Fe–S) clusters are prosthetic groups ensuring electron transfer
reactions, activating substrates for catalytic reactions, providing sulfur atoms for the …
reactions, activating substrates for catalytic reactions, providing sulfur atoms for the …