Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

Salmonella enterica serovar Typhimurium is a primary enteric pathogen infecting both
humans and animals. Infection begins with the ingestion of contaminated food or water so …

The gastrointestinal tract (GIT) is lined by a layer of mucus formed by mucin glycoproteins.
This layer constitutes a physical and chemical barrier between the intestinal contents and …

Intestinal epithelial cells apically express glycans, especially α1, 2-fucosyl linkages, which
work as a biological interface for the host–microbe interaction. Emerging studies have …

The DNA adenine methyltransferase (Dam methylase) of Gammaproteobacteria and the cell
cycle-regulated methyltransferase (CcrM) methylase of Alphaproteobacteria catalyze an …

The lower gastrointestinal tract is densely populated with resident microbial communities
(microbiota), which do not elicit overt host responses but rather provide benefit to the host …

Salmonella enterica species are Gram-negative bacteria, which are responsible for a wide
range of food-and water-borne diseases in both humans and animals, thereby posing a …

During weaning, infants and young animals are susceptible to severe enteric infections, thus
inducing intestinal microbiota dysbiosis, intestinal inflammation, and impaired intestinal …

The std operon encodes a fimbrial adhesin of Salmonella enterica serotype Typhimurium
that is required for attachment to intestinal epithelial cells and for cecal colonization in the …

Hosts are protected from attack by potentially harmful enteric microorganisms, viruses, and
parasites by the polarized fully differentiated epithelial cells that make up the epithelium …