Obesity and cardiovascular disease: revisiting an old relationship
C Koliaki, S Liatis, A Kokkinos - Metabolism, 2019 - Elsevier
A wealth of clinical and epidemiological evidence has linked obesity to a broad spectrum of
cardiovascular diseases (CVD) including coronary heart disease, heart failure …
cardiovascular diseases (CVD) including coronary heart disease, heart failure …
Relevance of leptin and other adipokines in obesity-associated cardiovascular risk
MF Landecho, C Tuero, V Valentí, I Bilbao… - Nutrients, 2019 - mdpi.com
Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …
Resveratrol and vascular function
Resveratrol increases the production of nitric oxide (NO) in endothelial cells by upregulating
the expression of endothelial NO synthase (eNOS), stimulating eNOS enzymatic activity, and …
the expression of endothelial NO synthase (eNOS), stimulating eNOS enzymatic activity, and …
Obesity and COVID-19: molecular mechanisms linking both pandemics
The coronavirus disease 2019 COVID-19 pandemic is rapidly spreading worldwide and is
becoming a major public health crisis. Increasing evidence demonstrates a strong …
becoming a major public health crisis. Increasing evidence demonstrates a strong …
New therapeutic implications of endothelial nitric oxide synthase (eNOS) function/dysfunction in cardiovascular disease
The Global Burden of Disease Study identified cardiovascular risk factors as leading causes
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
Circadian rhythm, clock genes, and hypertension: recent advances in hypertension
HM Costello, ML Gumz - Hypertension, 2021 - Am Heart Assoc
Accumulating evidence suggests that the molecular circadian clock is crucial in blood
pressure (BP) control. Circadian rhythms are controlled by the central clock, which resides in …
pressure (BP) control. Circadian rhythms are controlled by the central clock, which resides in …
The role of obesity-induced perivascular adipose tissue (PVAT) dysfunction in vascular homeostasis
A Stanek, K Brożyna-Tkaczyk, W Myśliński - Nutrients, 2021 - mdpi.com
Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …
Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice
P Lang, S Hasselwander, H Li, N Xia - Scientific Reports, 2019 - nature.com
The aim of the present study was to compare different diets used to induce obesity in a head-
to-head manner with a focus on insulin resistance and vascular dysfunction. Male C57BL/6J …
to-head manner with a focus on insulin resistance and vascular dysfunction. Male C57BL/6J …
Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease
Obesity and diabetes are strongly associated with metabolic and cardiovascular disorders
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …