Hypothalamus and post-traumatic stress disorder: a review

P Raise-Abdullahi, M Meamar, AA Vafaei, M Alizadeh… - Brain sciences, 2023 - mdpi.com
Humans have lived in a dynamic environment fraught with potential dangers for thousands
of years. While fear and stress were crucial for the survival of our ancestors, today, they are …

Central regulation of metabolism by growth hormone

J Donato Jr, F Wasinski, IC Furigo, M Metzger… - Cells, 2021 - mdpi.com
Growth hormone (GH) is secreted by the pituitary gland, and in addition to its classical
functions of regulating height, protein synthesis, tissue growth, and cell proliferation, GH …

Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons

IC Furigo, PDS Teixeira, GO de Souza… - Nature …, 2019 - nature.com
Weight loss triggers important metabolic responses to conserve energy, especially via the
fall in leptin levels. Consequently, weight loss becomes increasingly difficult with weight …

Growth hormone action in somatostatin neurons regulates anxiety and fear memory

WO Dos Santos, VAL Juliano, FM Chaves… - Journal of …, 2023 - Soc Neuroscience
Dysfunctions in growth hormone (GH) secretion increase the prevalence of anxiety and
other neuropsychiatric diseases. GH receptor (GHR) signaling in the amygdala has been …

New findings on brain actions of growth hormone and potential clinical implications

J Donato Jr, JJ Kopchick - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
Growth hormone (GH) is secreted by somatotropic cells of the anterior pituitary gland. The
classical effects of GH comprise the stimulation of cell proliferation, tissue and body growth …

Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus

RSE Brown, IC Kokay, HR Phillipps, SH Yip… - Journal of …, 2016 - Soc Neuroscience
Tuberoinfundibular dopamine (TIDA) neurons, known as neuroendocrine regulators of
prolactin secretion from the pituitary gland, also release GABA within the hypothalamic …

Analysis of prolactin receptor expression in the murine brain using a novel prolactin receptor reporter mouse

IC Kokay, A Wyatt, HR Phillipps, M Aoki… - Journal of …, 2018 - Wiley Online Library
Prolactin influences a wide range of physiological functions via actions within the central
nervous system, as well as in peripheral tissues. A significant limitation in studies …

Understanding the role of growth hormone in situations of metabolic stress

MR Tavares, R Frazao, J Donato - Journal of Endocrinology, 2023 - joe.bioscientifica.com
Growth hormone (GH) is secreted by the anterior pituitary gland and plays a key role in
controlling tissue and body growth. While basal GH secretion is considerably reduced along …

Effects of the isolated and combined ablation of growth hormone and IGF-1 receptors in somatostatin neurons

FM Chaves, F Wasinski, MR Tavares… - …, 2022 - academic.oup.com
Hypophysiotropic somatostatin (SST) neurons in the periventricular hypothalamic area
express growth hormone (GH) receptor (GHR) and are frequently considered as the key …

[HTML][HTML] Effects of growth hormone in the central nervous system

F Wasinski, R Frazão, J Donato - Archives of endocrinology and …, 2020 - SciELO Brasil
Growth hormone (GH) is best known for its effect stimulating tissue and somatic growth
through the regulation of cell division, regeneration and proliferation. However, GH …