Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

This article will provide an updated review of spermatogonial stem cells and their role in
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …

Mammalian male germ-cell development consists of three distinct phases: primordial germ
cell (PGC) development, male germ-cell specification for spermatogonium development …

Spermatogonial stem cells (SSCs) can produce numerous male gametes after
transplantation into recipient testes, presenting a valuable approach for gene therapy and …

Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

Mammalian spermatogenesis is a classic adult stem cell–dependent process, supported by
self-renewal and differentiation of spermatogonial stem cells (SSCs). Studying SSCs …

Embryonic germ cells as well as germline stem cells from neonatal mouse testis are
pluripotent and have differentiation potential similar to embryonic stem cells,, suggesting that …

Although germline cells can form multipotential embryonic stem (ES)/embryonic germ (EG)
cells, these cells can be derived only from embryonic tissues, and such multipotent cells …

Spermatogenesis, a study of germ cell development, is a long, orderly, and well‐defined
process occurring in seminiferous tubules of the testis. It is a temporal event whereby …

Adult mammalian testis is a source of pluripotent stem cells. However, the lack of specific
surface markers has hampered identification and tracking of the unrecognized subset of …