Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …
has been one of the most significant biochemical and pharmacological advancements to …
Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids
KA Seely, J Lapoint, JH Moran, L Fattore - Progress in Neuro …, 2012 - Elsevier
“K2” and “Spice” drugs (collectively hereafter referred to as Spice) represent a relatively new
class of designer drugs that have recently emerged as popular alternatives to marijuana …
class of designer drugs that have recently emerged as popular alternatives to marijuana …
Towards the use of cannabinoids as antitumour agents
Various reports have shown that cannabinoids (the active components of marijuana and
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …
Assessment of antiviral potencies of cannabinoids against SARS-CoV-2 using computational and in vitro approaches
V Raj, JG Park, KH Cho, P Choi, T Kim, J Ham… - International journal of …, 2021 - Elsevier
Effective treatment choices to the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) are limited because of the absence of effective target-based therapeutics. The main …
CoV-2) are limited because of the absence of effective target-based therapeutics. The main …
[HTML][HTML] Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors
Inflammation in the central nervous system (CNS) is a complex process that involves a
multitude of molecules and effectors, and it requires the transmigration of blood leukocytes …
multitude of molecules and effectors, and it requires the transmigration of blood leukocytes …
The current state and future perspectives of cannabinoids in cancer biology
P Śledziński, J Zeyland, R Słomski… - Cancer medicine, 2018 - Wiley Online Library
To date, cannabinoids have been allowed in the palliative medicine due to their analgesic
and antiemetic effects, but increasing number of preclinical studies indicates their anticancer …
and antiemetic effects, but increasing number of preclinical studies indicates their anticancer …
Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?
Prenatal exposure to infection and subsequent inflammatory responses have been
implicated in the etiology of schizophrenia and autism. In this review, we summarize current …
implicated in the etiology of schizophrenia and autism. In this review, we summarize current …
Cannabis impacts tumor response rate to nivolumab in patients with advanced malignancies
Background There has been a significant increase in the use of immunotherapy and
cannabis recently, two modalities that have immunomodulatory effects and may have …
cannabis recently, two modalities that have immunomodulatory effects and may have …
The endocannabinoid system and physical exercise
The endocannabinoid system (ECS) is involved in various processes, including brain
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …
Cannabinoid receptor 2: potential role in immunomodulation and neuroinflammation
S Rom, Y Persidsky - Journal of Neuroimmune Pharmacology, 2013 - Springer
An accumulating body of evidence suggests that endocannabinoids and cannabinoid
receptors type 1 and 2 (CB 1, CB 2) play a significant role in physiologic and pathologic …
receptors type 1 and 2 (CB 1, CB 2) play a significant role in physiologic and pathologic …