The development of the vertebrate central nervous system is reliant on a complex cascade
of biological processes that include mitotic division, relocation of migrating neurons, and the …

Myelin sheath geometry, encompassing myelin sheath thickness relative to internodal
length, is critical to optimize nerve conduction velocity and these parameters are carefully …

Circulation of the cerebrospinal fluid (CSF) contributes to body axis formation and brain
development. Here, we investigated the unexplained origins of the CSF flow bidirectionality …

Despite decades of study, elucidation of the underlying etiology of complex developmental
disorders such as autism spectrum disorder (ASD), schizophrenia (SCZ), intellectual …

Abstract Zinc oxide nanoparticles (ZnO NPs) have been increasingly and widely utilized in
various fields, such as agriculture, food and cosmetics. However, various levels of adverse …

Hippo signaling, an evolutionarily conserved kinase cascade involved in organ size control,
plays key roles in various tissue developmental processes, but its role in craniofacial …

A fundamental issue in nervous system development and homeostasis is to understand the
mechanisms governing the balance between the maintenance of proliferating progenitors …

Primary neurulation is the process by which the neural tube, the central nervous system
precursor, is formed from the neural plate. Incomplete neural tube closure occurs frequently …

Periconception maternal folic acid (vitamin B 9) supplementation can reduce the prevalence
of neural tube defects (NTDs), although just how folates benefit the developing embryo and …

Developmental neurotoxicity entails one of the most complex areas in toxicology. Animal
studies provide only limited information as to human relevance. A multitude of alternative …